Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/1219
Título: Association of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goat
Autor: Marques, P. X.
Pereira, M.
Marques, M. Rosário
Santos, Ingrid
Belo, Carmona
Renaville, Robert
Cravador, A.
Palavras-chave: Single strand conformation polymorphism
Genetic markers
Growth hormone
Goat
Milk traits
Data: 2003
Citação: Marques, P. X.; Pereira, M.; Marques, M. Rosário; Santos, Ingrid; Belo, Carmona; Renaville, Robert; Cravador, Alfredo. Association of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goat. Small Ruminant Research, 50, 1-2, 177-185, 2003.
Resumo: The present study suggests the existence of an association between milk production traits and genetic polymorphisms at the growth hormone (GH) gene in the Portuguese indigenous Serrana goat. TheDNAfrom 229 animals of two ecotypes (Jarmelista and Ribatejano)was analysed by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique revealing a high degree of genetic polymorphism at the goat GH (gGH) gene. Two conformation patterns were detected in exons 1 and 2, 6 in exon 3, 10 in exon 4 and 5 in exon 5. The evaluation of an association effect between these SSCP patterns with milk, fat and protein yields and fat and protein percentages suggests a positive effect of pattern A/B of exon 4 for Ribatejano ecotype and of pattern A/B of exon 2 for Jarmelista ecotype with milk yield (P < 0.05) and of pattern A/B of exon 1 and pattern B/B of exon 2 with protein percentage (P < 0.05) for Ribatejano ecotype. The results support the hints suggested by previous studies of the importance of the gGH gene as a candidate gene for marker-assisted selection in goat breeds and suggest that exon 4 is a preferential target for further investigation on mutations that influence milk yield variation.
Peer review: yes
URI: http://hdl.handle.net/10400.1/1219
ISSN: 0921-4488
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