Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/2558
Título: Antimicrobial activity of Drosophyllum lusitanicum, an endemic Mediterranean insectivorous plant
Autor: Gonçalves, Sandra
Quintas, Célia
Gaspar, Maria Nelma
Nogueira, José Manuel F.
Romano, Anabela
Palavras-chave: Antimicrobial activity
Bacteria
Human
Pathogens
Plant extract
Plumbagin
Yeasts
Data: 2009
Citação: Gonçalves S., Quintas C., Gaspar M. N., Nogueira J. M. F, Romano A. 2009. Antimicrobial activity of Drosophyllum lusitanicum leaf extract, an endemic Mediterranean insectivorous plant, Natural Product Research 23: 119-129
Resumo: The aim of this study was to evaluate the antimicrobial activity of Drosophyllum lusitanicum leaf extract against various yeasts and bacteria species, including both standard and clinically isolated strains. The extract exhibited strong antimicrobial activity against all the tested yeast strains with inhibition zones ranging 23.67–42.23mm and with minimum inhibitory concentration (MIC) values ranging 31–63 mgL 1. All the Gram-positive bacteria studied were inhibited by the extract, showing inhibition zones ranging 17.67–43.00mm and MIC values comprising between 15.6 and 250 mgL 1. In contrast, the growth of the tested Gram-negative bacteria was not significantly affected by the extract. Among the microorganisms tested, Staphylococcus epidermidis ATCC 12228 was the most sensitive, presenting the lowest MIC value (15.6 mgL 1), while Enterococcus faecalis ATCC 29212 was the most tolerant (250 mgL 1). The extract of D. lusitanicum was analysed by gas chromatography-mass spectrometry and the major constituent found was plumbagin.
Peer review: yes
URI: http://hdl.handle.net/10400.1/2558
ISSN: 1478-6419
Versão do Editor: http://www.tandfonline.com/doi/abs/10.1080/14786410801972870?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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