Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/4604
Título: Decavanadate contribution to vanadium biochemistry: In vitro and in vivo studies
Autor: Aureliano, M.
Palavras-chave: Decavanadate
Vanadate
Vanadyl
Myosin
Actin
Ca2+-ATPase
Data: 2014
Editora: Elsevier
Resumo: Although the number of papers about ‘‘decavanadate’’ has increased in the last decade invivo or/and cellular toxicological studies involving vanadium that takes in account the contribution of decavanadate (V10) ion species to biological responses are scarce. These innovative in vivo studies are supported by the fact that decavanadate interact with major proteins such as myosin, actin and Ca2+-ATPase and affect mitochondria function besides induces changes in several cellular antioxidants markers. These recent findings, that are now briefly reviewed, suggested that the biological responses induced by vanadium, will be dependent on vanadium ion species such as decavanadate. Putting it all together, it is clearly shown that decavanadate can be involved in many cellular processes, and therefore it must be taken in account for the understanding the role of vanadium in biological systems.
Peer review: yes
URI: http://hdl.handle.net/10400.1/4604
DOI: http://dx.doi.org/ 10.1016/j.ica.2013.10.010
ISSN: 0020-1693
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S0020169313005744
Aparece nas colecções:FCT2-Artigos (em revistas ou actas indexadas)

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