Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/4776
Título: Vanadate oligomer inhibition of passive and active Ca2+ translocation by the Ca2+ pump of sarcoplasmic reticulum
Autor: Aureliano, M.
Palavras-chave: Decavanadate
Calcium ATPase
Sarcoplasmic reticulum
Data: 30-Mai-2000
Editora: Elsevier
Resumo: ‘Monovanadate’ containing mainly monomeric, dimeric and tetrameric vanadate species or ‘decavanadate’, containingmainlydecameric vanadate species inhibits the passive and the active efflux of Ca2+ through the sarcoplasmic reticulum calcium pump. When the efflux of Ca2+ by sarcoplasmic reticulum vesicles is not associated with ATP synthesis both vanadate solutions inhibit the passive efflux of Ca 2+. However, only ‘decavanadate’ exerts noticeable effects when the efflux of Ca2q is associated with ATP synthesis being the active efflux of Ca2+ almost completely inhibited by decameric species concentration as low as 40 microM.
Peer review: yes
URI: http://hdl.handle.net/10400.1/4776
ISSN: 0162-0134
Versão do Editor: http://ac.els-cdn.com/S0162013400000222/1-s2.0-S0162013400000222-main.pdf?_tid=0149b7ce-0c10-11e4-b78e-00000aacb35e&acdnat=1405422547_43667c8077cb759a319adb2504f76266
Aparece nas colecções:FCT2-Artigos (em revistas ou actas indexadas)

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