Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/4978
Título: Synthetic versus natural receptors: supramolecular control of chemical sensing in fish
Autor: Silva, José P. da
Choudhury, Rajib
Porel, Mintu
Pischel, Uwe
Jockush, Steffen
Hubbard, Peter
Ramamurthy, Vaidhyanathan
Canario, Adelino V. M.
Palavras-chave: Synthetic
Natural receptors
Supramolecular control
Fish
Data: 19-Mai-2014
Editora: ACS Publications
Citação: José P. Da Silva, Rajib Choudhury, Mintu Porel, Uwe Pischel, Steffen Jockusch, Peter C. Hubbard,Vaidhyanathan Ramamurthy, and Adelino V. M. Canário. 2014, Synthetic versus natural receptors: supramolecular control of chemical sensing in fish, ACS Chemical Biology, 9, 1432-1436, dx.doi.org/10.1021/cb500172u
Resumo: The encapsulation of odorants by the synthetic receptor cucurbit[7]uril (CB[7]) reduces the response of olfactory receptors in Mozambique tilapia (Oreochromis mossambicus) in vivo. For example, the olfactory receptor response to the odorant adamantan-1-amine, as measured by electro-olfactography, was suppressed by 92% in the presence of CB[7]. A reduction in olfactory response of 88% was observed for pentane-1,5-diamine (cadaverine), an odorant associated with carrion avoidance in some fish. The results reveal how the association constants and the concentrations of natural and synthetic receptors play a determinant role and show that synthetic receptors can be used to remove bioactive molecules from fish olfaction.
Peer review: yes
URI: http://hdl.handle.net/10400.1/4978
DOI: http://dx.doi.org/10.1021/cb500172u |
ISSN: 1554-8929
Versão do Editor: http://pubs.acs.org/doi/abs/10.1021/cb500172u
Aparece nas colecções:CCM2-Artigos (em revistas ou actas indexadas)



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