Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/5449
Título: Effects of the antithyroid agent propylthiouracil in a partial life cycle assay with zebrafish
Autor: Van der Ven, Leo
Van den Brandhof, Evert-Jan
Vos, José H.
Power, Deborah
Wester, Piet W.
Data: 2006
Editora: ACS Publications
Citação: Leo T.M . Vanderven, Evert-Jan Van den Brandhof, José H. Vos, Deborah Power, Piet W. Wester, "Effects of the antithyroid agent propylthiouracil in a partial life cycle assay with zebrafish" in Environ. Sci. Technol. 2006, 40, 74-81.
Resumo: Some ubiquitous pollutants of the aquatic environment, such as PCBs or other polyhalogenated aromatic hydrocarbons, may disrupt the thyroid hormone system. In a partial life cycle assay with zebrafish (Danio rerio), we studied the effects of the reference compound propylthiouracil (PTU) on reproduction, growth and development, histopathology of some target tissues, and plasma thyroid hormone levels. PTU induced a concentration-dependent increase of egg production with a concomitant decrease of mature oocyte size but had no effect on fertilization rate or hatching.
Peer review: yes
URI: http://hdl.handle.net/10400.1/5449
DOI: http://dx.doi.org/10.1021/es050972c
ISSN: 0013-936X
Aparece nas colecções:CCM2-Artigos (em revistas ou actas indexadas)



FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.