Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/6328
Título: Antioxidant, Anti-5-lipoxygenase and Antiacetylcholinesterase Activities of Essential Oils and Decoction Waters of Some Aromatic Plants
Autor: Albano, S. M.
Lima, A. S.
Miguel, Maria Graça
Pedro, L. G.
Barroso, J. G.
Figueiredo, A. C.
Data: 2012
Editora: ACG Publications
Resumo: The scavenging of free radicals and superoxide anion, the inhibition of 5-lipoxygenase and the antiacetylcholinesterase activities of essential oils and decoction waters of eight aromatic plants (Dittrichia viscosa, Foeniculum vulgare, Origanum vulgare, Salvia officinalis, Thymbra capitata, Thymus camphoratus, Thymus carnosus and Thymus mastichina) were studied. The essential oils were dominated by 1,8-cineole in S. officinalis (59%), T. mastichina (49%) and T. camphoratus (21%); borneol (20%) in T. carnosus; carvacrol in Thymbra capitata (68%); gamma-terpinene (49%) in O. vulgare; alpha-pinene (26%) in F. vulgare; and trans-nerolidol (8%) + beta-oplopenone (7%) in D. viscosa. O. vulgare decoction waters had the highest amount of phenols (45 +/- 3mg GAE/mL) while F. vulgare only had 5 +/- 0mg GAE/mL. The decoction waters showed higher radical scavenging activity than the essential oils. O. vulgare decoction water showed the best antioxidant activity (IC(50) = 3 +/- 0 mu g/mL), while the most effective essential oils were those of Thymbra capitata (IC(50) = 61 +/- 2 mu g/mL) and O. vulgare (IC(50) = 156 +/- 5 mu g/mL). Thymbra capitata (IC(50) = 6 +/- 0 mu g/mL) decoction water showed the best superoxide anion scavenging activity. F. vulgare decoction water and essential oil revealed the best 5-lipoxygenase inhibition capacity (IC(50) = 27 +/- 1 mu g/mL and IC(50) = 68 +/- 2 mu/mL, respectively). T. mastichina (IC(50) = 46 +/- 4 mu g/mL), S. officinalis (IC(50) = 51 +/- 4 mu g/mL), Thymbra capitata (IC(50) = 52 +/- 1 mu g/mL) and T. camphoratus (IC(50) = 137 +/- 2 mu g/mL) essential oils showed the best antiacetylcholinesterase activity.
Peer review: yes
URI: http://hdl.handle.net/10400.1/6328
ISSN: 1307-6167
Aparece nas colecções:FCT2-Artigos (em revistas ou actas indexadas)



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