Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/6407
Título: Phytochemical Profile, Antioxidant and Cytotoxic Activities of the Carob Tree (Ceratonia siliqua L.) Germ Flour Extracts
Autor: Custodio, L.
Escapa, A. L.
Fernandes, E.
Fajardo, A.
Aligue, R.
Albericio, F.
Neng, N. R.
Nogueira, J. M. F.
Romano, Anabela
Data: 2011
Editora: Springer
Resumo: This work aimed to evaluate the phytochemical content and to determine the antioxidant and cytotoxic activities of methanol extracts of the carob tree (Ceratonia siliqua L.) germ flour. The extracts were rich in phenolic compounds, had considerable antioxidant activity, and reduced the viability of cervical (HeLa) cancer cells. The chemical content and the biological activities of the extracts were significantly affected by gender and cultivar. Female cultivar Galhosa had the highest levels of phenolic compounds, and the highest antioxidant activity. Extracts from the hermaphrodite trees and from the female cultivars Galhosa and Costela/Canela exhibited the highest cytotoxic activity. The most abundant compound was theophylline. The phenolic content was correlated to both antioxidant and cytotoxic activities. Our findings provide new knowledge about the health implications of consuming food supplemented with carob germ flour.
Peer review: yes
URI: http://hdl.handle.net/10400.1/6407
DOI: https://dx.doi.org/10.1007/s11130-011-0214-8
ISSN: 0921-9668
Aparece nas colecções:FCT2-Artigos (em revistas ou actas indexadas)



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