Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/7385
Título: Antioxidant and anti-cholinesterase activities of Lavandula viridis L’Hér extracts after in vitro gastrointestinal digestion
Autor: Costa, Patrícia
Grevenstuk, Tomás
Costa, Ana M. Rosa da
Gonçalves, Sandra
Romano, Anabela
Palavras-chave: Lavandula viridis
Rosmarinic acid
In vitro digestion
Antioxidant activity
Anti-cholinesterase activity
Data: Abr-2014
Editora: Elsevier
Citação: Ind Crop Prod, 55 (2014) 83–89
Resumo: Lavandula viridis L’Hér is an aromatic shrub with relevant biological activities associated to the presence ofphenolic compounds. However, these compounds must be bioavailable to exert their biological function.Therefore, in this study, we investigated the influence of the L. viridis extract matrices on the digestion ofthe main component rosmarinic acid and their antioxidant and anti-cholinesterase activities after in vitrogastrointestinal digestion. Overall, the antioxidant and anti-cholinesterase activities were assured afterin vitro gastrointestinal processes and we observed that the L. viridis extract matrices have an importantrole in the bioactive effects of their main compound, rosmarinic acid. The L. viridis extracts and rosmarinicacid did not show any toxic effect on colon adenocarcinoma Caco-2 cell viability. Finally, the compoundsfrom L. viridis extracts were not metabolized by Caco-2 cells and were not able to permeate into them.
Peer review: yes
URI: http://hdl.handle.net/10400.1/7385
DOI: http://dx.doi.org/10.1016/j.indcrop.2014.01.049
ISSN: 0926-6690
Versão do Editor: http://ac.els-cdn.com/S0926669014000703/1-s2.0-S0926669014000703-main.pdf?_tid=5d2e71c6-e724-11e3-84b1-00000aab0f6c&acdnat=1401363092_c431b799a84c1d03801851bbb022e03c
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