Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.1/2583
Título: Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér
Autor: Costa, Patrícia
Grosso, Clara
Gonçalves, Sandra
Andrade, Paula B.
Valentão, Patrícia
Bernardo-Gil, Maria Gabriela
Romano, Anabela
Palavras-chave: Lavandula viridis
Essential oil
SFE extracts
Antioxidants
Anti-cholinesterase
Alzheimer’s disease
Data: 2012
Citação: Costa P., Grosso C., Gonçalves S., Andrade P. B., Valentão P., Romano A 2012. Supercritical fluid extraction and hydrodistillation for the recovery of bioactive compounds from Lavandula viridis L’Hér, Food Chemistry 135: 112–121
Resumo: The chemical profiles of bioactive essential oil and extracts obtained by hydrodistillation (HD) and supercritical fluid extraction (SFE), respectively, from Lavandula viridis were compared. The SFE was performed at 40 C and at extraction pressures of 12 or 18 MPa in two different separators. Evaluation of the essential oil and SFE extracts by GC–FID and GC–IT–MS revealed that oxygen-containing monoterpenes were the major constituents in both cases, but there were important differences between the chemical profiles produced by the different extraction techniques. More compounds were isolated by HD but higher yields were achieved by SFE. Camphor was the main component identified in the essential oil (31.59 ± 1.32%), and in extracts from the first (1.61 ± 0.34%) and second SFE separators (22.48 ± 1.49%) at 12 MPa. In contrast, the first separator SFE extract at 18 MPa (heavy compounds) was dominated by myrtenol(5.38 ± 2.04%) and camphor (4.81 ± 1.93%), whereas the second separator SFE extract (volatiles) was dominated by verbenone (13.97 ± 5.27%). The essential oil and heavy compound extracts from the first separator possessed antioxidant and anti-cholinesterase activities. Our data show that phytochemicals from the aerial parts of L. viridis could be developed as natural antioxidant and anti-cholinesterase drugs, with particular applications in the symptomatic treatment of Alzheimer’s disease.
Peer review: yes
URI: http://hdl.handle.net/10400.1/2583
ISSN: 0308-8146
Versão do Editor: http://www.sciencedirect.com/science/article/pii/S0308814612007716
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