Catamo Vaz, Deise Haua da SilvaCosta, Maria Helena daBuque, Helena AgostinhoNzwalo, Hipólito2024-10-212024-10-212024-110022-510Xhttp://hdl.handle.net/10400.1/26117We read with great interest the manuscript by Spencer et al. [1] suggesting a possible role of Methyl-CpG-binding protein 2 (MECP2) dysregulation in the pathogenesis of Nodding syndrome (NS), a childhood onset epileptic disorder occurring exclusively in sub-Saharan Africa. The sociodemographic and phenotypic overlap of NS with MECP2 duplication syndrome, namely the age of onset interval, female predominance;engMECP2Nodding syndromeMycotoxinsMozambiqueletter to the editor10.1016/j.jns.2024.1232611878-5883