Canario, Adelino V. M.Flik, G.2014-05-152014-05-152007Canario, Adelino; Flik, Gert. Endocrinology of calcium homeostasis, General and Comparative Endocrinology, 152, 2-3, 242-242, 2007.0016-6480AUT: ACA00258;http://hdl.handle.net/10400.1/3976Michelle Wheatly reviewed the role of binding proteins in the regulation of calcium homeostasis during periods of net vectorial influx using the crayfish, Procambarus clarkii, as a model. The protein studied were the import and export proteins, epithelial Ca2+ channel (ECaC), sarco/endoplasmic reticulum Ca2+ ATPase (SERCA), plasma membrane Ca2+ ATPase (PMCA) and Na+/Ca2+ exchanger (NCX). The expression of these proteins is a coordinated process at multiple levels including the apical vs. basolateral domains, plasma membranes vs. organelle membranes and transmembrane Ca2+ transporters and binding proteins. An integrative model of cellular Ca2+ homeostasis was presented which took into account the spatial and temporal protein expression during crayfish molting.englecture2014-05-08http://dx.doi.org/10.1016/j.ygcen.2007.05.023