Peres dos Santos, R.Bensimon-Brito, A.Gavaia, Paulo J.Cancela, Leonor2014-06-242014-06-242009Peres dos Santos R., Bensimon-Brito A., Gavaia P., Cancela M.L. 2009. Warfarin effects in the skeletal development of zebrafish (Danio rerio). Interdisciplinary Approaches in Fish Skeletal Biology, April 27 – 29 Tavira, Portugal.AUT: LCA00739http://hdl.handle.net/10400.1/4467The vitamin K-dependent (VKD) gamma-glutamyl carboxylase promotes the conversion of glutamic acid residues (Glu) to gamma-carbolxyglutamic acid (Gla) in a post translational modification that is essential for the functionality of VKD proteins. This process affects homeostasis, apoptosis, signal transduction, growth control, arterial calcification and bone development.engconference object