Frija, L.Khmelinskii, IgorCristiano, Maria Lurdes Santos2014-06-062014-06-062005Frija, Luís M.T.; Khmelinskii, Igor V.; Cristiano, M. Lurdes S.Novel efficient synthesis of 3,4-dihydro-6-substituted-3-phenylpyrimidin-2(1H)-ones, Tetrahedron Letters, 46, 39, 6757-6760, 2005.0040-4039AUT: IKH00165; MCR00716;http://hdl.handle.net/10400.1/4214A new attractive and convenient strategy for the synthesis of 3,4-dihydro-6-substituted-3-phenylpyrimidin-2(1H)-ones is described. Photolysis (k = 254 nm) of 4-allyl-tetrazolones in alcoholic solutions produces the corresponding pyrimidinones as the sole product in nearly quantitative yields, with simultaneous extrusion of molecular nitrogen. Work-up procedures consist in the simple evaporation of the solvent under reduced pressure, in mild conditions. Heats of reaction for the photocleavage process of 4-allyltetrazolones were calculated, indicating high stability of the resulting products.engTetrazolesPyrimidinonesPhotolysisAllyl alcoholsTetrazolonesjournal article2014-06-05http://dx.doi.org/10.1016/j.tetlet.2005.07.101