Miguel, Maria GraçaBarroso, J. G.2015-06-152015-06-1519940031-9422AUT: MGM00322;http://hdl.handle.net/10400.1/6282Cell suspension cultures of Hyoscyamus albus treated with freeze-dried Phytophthora cinnamomi autoclaved mycelium of freeze-dried Candida albicans autoclaved cells accumulated mainly lubimin and 10-epilubimun, along with small amounts of rishitin and solavetivone. Cultures treated with cellulase did not accumulate any of the reported compounds. The pattern and the amount of sesquiterpenoids produced were dependent on cell growth stage, incubation time with the elicitor and elicitor concentration. Higher yields of lubimin and 10-epilubimin occurred in cultures inoculated two days after subculturing and incubated for 48 hr. Some elicitor-treated cultures and old untreated ones accumulated acetophenones: acetovanillone, acetosyringone and hydroxyacetosyringone.engAccumulation of stress metabolites in cell-suspension cultures of hyoscyamus-albusjournal articlehttps://dx.doi.org/10.1016/S0031-9422(00)94766-6