Pereira, Nelson A. M.Lemos, A.Serra, Arménio C.Melo, Teresa M. V. D. Pinho e2014-12-152014-12-152013-03-20Pereira, Nelson A.M.; Lemos, Américo; Serra, Arménio C.; Pinho e Melo, Teresa M.V.D.Functionalization of dipyrromethanes via hetero-Diels–Alder reaction with azo- and nitrosoalkenes, Tetrahedron Letters, 54, 12, 1553-1557, 2013.0040-4039AUT: ALE01411http://hdl.handle.net/10400.1/56875,50-Diethyl- and 5-phenyldipyrromethanes participate in cycloadditions with azo- and nitrosoalkenes giving dipyrromethanes with side chains containing open chain oximes and hydrazones. By controlling reaction stoichiometry it is possible to get mono or 1,9-disubstituted derivatives. The reported methodology gave access to a range of dipyrromethanes with good structural features for various applications. It was demonstrated that reduction of dipyrromethanes containing a-oximino ester groups opens the way to new a-amino esters.engDipyrromethanesAzoalkenesNitrosoalkenesHetero-Diels–Alder reactionjournal article2014-12-11