Publication
Experimental infection of European flat oyster Ostrea edulis with ostreid herpesvirus 1 microvar (OsHV-1 mu var): Mortality, viral load and detection of viral transcripts by in situ hybridization
| dc.contributor.author | Sanmartin, Monserrat Lopez | |
| dc.contributor.author | Power, Deborah | |
| dc.contributor.author | de la Herran, Roberto | |
| dc.contributor.author | Navas, Jose I. | |
| dc.contributor.author | Batista, Frederico | |
| dc.date.accessioned | 2017-04-07T15:56:30Z | |
| dc.date.available | 2017-04-07T15:56:30Z | |
| dc.date.issued | 2016-06 | |
| dc.description.abstract | Ostreid herpesvirus 1 (OsHV-1) infections have been reported in several bivalve species. Mortality of Pacific oyster Crassostrea gigas spat has increased considerably in Europe since 2008 linked to the spread of a variant of OsHV-1 called var. In the present study we demonstrated that O. edulis juveniles can be infected by OsHV-1 mu var when administered as an intramuscular injection. Mortality in the oysters injected with OsHV-1 mu var was first detected 4 days after injection and reached 25% mortality at day 10. Moreover, the high viral load observed and the detection of viral transcripts by in situ hybridization in several tissues of dying oysters suggested that OsHV-1 mu var was the cause of mortality in the O. edulis juveniles. This is therefore the first study to provide evidence about the pathogenicity of OsHV-1 var in a species that does not belong to the Crassostrea genus. Additionally, we present a novel method to detect OsHV-1 transcripts in infected individuals' using in situ hybridization. (C) 2016 Elsevier B.V. All rights reserved. | |
| dc.identifier.doi | 10.1016/j.virusres.2016.01.023 | |
| dc.identifier.issn | 0168-1702 | |
| dc.identifier.issn | 0168-1702 | |
| dc.identifier.other | AUT: DPO00386; | |
| dc.identifier.uri | http://hdl.handle.net/10400.1/9432 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | Elsevier | |
| dc.relation.isbasedon | WOS:000375498900008 | |
| dc.title | Experimental infection of European flat oyster Ostrea edulis with ostreid herpesvirus 1 microvar (OsHV-1 mu var): Mortality, viral load and detection of viral transcripts by in situ hybridization | |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 62 | |
| oaire.citation.startPage | 55 | |
| oaire.citation.title | Virus Research | |
| oaire.citation.volume | 217 | |
| person.familyName | Power | |
| person.familyName | Batista | |
| person.givenName | Deborah Mary | |
| person.givenName | Frederico | |
| person.identifier.ciencia-id | 891A-8A44-3CAE | |
| person.identifier.ciencia-id | CB1B-7DBC-6303 | |
| person.identifier.orcid | 0000-0003-1366-0246 | |
| person.identifier.orcid | 0000-0002-2848-3011 | |
| person.identifier.rid | F-5651-2010 | |
| person.identifier.scopus-author-id | 7101806760 | |
| person.identifier.scopus-author-id | 7003808684 | |
| rcaap.rights | restrictedAccess | |
| rcaap.type | article | |
| relation.isAuthorOfPublication | c68f5ffb-63f6-4c70-8957-29e464fb59c0 | |
| relation.isAuthorOfPublication | d564e68d-a75e-458f-add4-bdb0739cde8d | |
| relation.isAuthorOfPublication.latestForDiscovery | d564e68d-a75e-458f-add4-bdb0739cde8d |
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