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Antibacterial activity of Moroccan Zantaz Honey and the influence of its physicochemical parameters using chemometric tools

dc.contributor.authorElamine, Youssef
dc.contributor.authorImtara, Hamada
dc.contributor.authorMiguel, Maria
dc.contributor.authorAnjos, Ofélia
dc.contributor.authorEstevinho, Letícia M.
dc.contributor.authorAlaiz, Manuel
dc.contributor.authorGirón-Calle, Julio
dc.contributor.authorVioque, Javier
dc.contributor.authorMartín, Jesús
dc.contributor.authorLyoussi, Badiâa
dc.date.accessioned2021-05-27T09:31:03Z
dc.date.available2021-05-27T09:31:03Z
dc.date.issued2021-05-20
dc.date.updated2021-05-24T15:03:49Z
dc.description.abstractThe emergence of multidrug-resistant bacteria has prompted the development of alternative therapies, including the use of natural products with antibacterial properties. The antibacterial properties of Zantaz honey produced in the Moroccan Atlas Mountains against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was evaluated and analyzed using chemometric tools. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) against S. aureus were the lowest (112.5 ± 54.5 mg/mL), revealing that this species was most sensitive to Zantaz honey. P. aeruginosa showed an intermediate sensitivity (MIC= 118.75 ± 51.9 mg/mL), while E. coli was the most resistant to treatment (MIC = 175 ± 61.2 mg/mL). Content of monosaccharides, certain minerals, and phenolic compounds correlated with antibacterial activity (p < 0.05). Principal component analysis of physicochemical characteristics and antibacterial activity indicated that the parameters most associated with antibacterial activity were color, acidity, and content of melanoidins, fructose, epicatechin, methyl syringate, 4-coumaric acid, and 3-coumaric acid.pt_PT
dc.description.sponsorshipUIDB/00239/2020, UIDB/05183/2020pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationApplied Sciences 11 (10): 4675 (2021)pt_PT
dc.identifier.doi10.3390/app11104675pt_PT
dc.identifier.eissn2076-3417
dc.identifier.urihttp://hdl.handle.net/10400.1/15508
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBupleurum spinosumpt_PT
dc.subjectMethyl syringatept_PT
dc.subjectEscherichia colipt_PT
dc.subjectPseudomonas aeruginosapt_PT
dc.subjectStaphylococcus aureuspt_PT
dc.titleAntibacterial activity of Moroccan Zantaz Honey and the influence of its physicochemical parameters using chemometric toolspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue10pt_PT
oaire.citation.startPage4675pt_PT
oaire.citation.titleApplied Sciencespt_PT
oaire.citation.volume11pt_PT
person.familyNameMiguel
person.givenNameMaria da Graça
person.identifier.ciencia-id6110-6FE7-DF28
person.identifier.orcid0000-0003-2507-4228
person.identifier.scopus-author-id35562054500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2507350f-9e60-4d4a-a096-53e58d93549c
relation.isAuthorOfPublication.latestForDiscovery2507350f-9e60-4d4a-a096-53e58d93549c

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