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Análises clínicas associadas a anemia
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Abstract(s)
A anemia é uma doença causada pela diminuição de hemoglobina no organismo . A hemoglobina é uma proteína localizada dentro dos glóbulos vermelhos, que possui o ferro responsável por levar o oxigénio aos tecidos. Existem vários tipos de anemia, causados por uma enorme variedade de factores.
À diminuição da hemoglobina estão acopladas características morfológicas dos glóbulos vermelhos que ajudam a distinguir os vários tipos de anemia. Outras características celulares para além destas, bem como dados bioquímicos, auxiliam a divisão de cada tipo de anemia nos seus subtipos
Neste trabalho procedeu-se à quantificação automática de parâmetros hematológicos e bioquimicos em 99 pacientes (59 mulheres e 40 homens), com idade média de 57± 25 anos e fez-se o diagnóstico dos tipos e subtipos de anemia presentes nesta população..
A média da concentração de hemoglobina destes pacientes, teve um valor mais baixo nos homens do que nas mulheres representando anemias maioritariamente leves nas mulheres e moderadas nos homens.
A população é essencialmente caracterizada por anemia microcitica-hipocrómica. Neste grupo verificou-se que a maioria da população era portadora de uma concentração de ferro e de ferritina diminuídas, sugerindo que a maioria dos pacientes deste grupo sofram de anemia ferropénica. No grupo de anemias normocitico-normocrómicas foi mais abundante a anemia ferropénica nas mulheres e as anemias de doenças crónicas nos homens. As anemias macrociticas foram bastante raras.
A população é então maioritariamente composta por anemias ferropénicas (49,5% dos pacientes), onde se obteve concentrações de ferro e ferritina mais baixos, 19,79 ± 7,64 µg/dl e 6,75 ± 3,48 µg/dl respectivamente, talassémias em 16,2% dos pacientes e doenças crónicas (12,1% dos pacientes), onde a ferritina apresentou valores mais elevados ( 413,14 ± 218,99 µg/dl).
Anemia is a disease caused by the decrease of hemoglobin in the body. Hemoglobin is a protein inside the red blood cells, which has the iron responsible for bringing oxygen to tissues. There are several types of anemia, caused by a variety factors With the decrease of haemoglobin are coupled morphological characteristics of red blood cells that help distinguish the various types of anemia. Other features in addition to these cellular and biochemical data, helping the division of each type of anemia in their subtypes. In this work, proceeded to the automatic quantification of biochemical and haematological parameters in 99 patients (59 women and 40 men) with an average age of 57 ± 25 years and gave up the diagnosis of type and subtypes of anemia in these population. The average concentration of haemoglobin in these patients had a lower worth in men than in women, representing mostly mild anemia in women and moderate in men. The population is mainly characterized by microcitic-hipochromic anemia. In this group found that the majority of population was carrying an iron and ferritin decreased, suggesting that the majority of this group of patients suffering from ferropenic anemia. In the group normocitic-normochromic, ferropenic anemia was the most abundant in women and chronic disease anemia in men. The macrocitic anemia were very rare. The population is now mostly composed of ferropenic anemia (49,5% of patients), which presented concentrations of iron and ferritin lowest, 19,79 ± 7,64 µg/dl and 6,75 ± 3,48 µg/dl respectively, thalassemias in 16,2% of patients and chronic diseases (12,1% of patients), which has the highest ferritin (413,14 ± 218,99 µg/dl).
Anemia is a disease caused by the decrease of hemoglobin in the body. Hemoglobin is a protein inside the red blood cells, which has the iron responsible for bringing oxygen to tissues. There are several types of anemia, caused by a variety factors With the decrease of haemoglobin are coupled morphological characteristics of red blood cells that help distinguish the various types of anemia. Other features in addition to these cellular and biochemical data, helping the division of each type of anemia in their subtypes. In this work, proceeded to the automatic quantification of biochemical and haematological parameters in 99 patients (59 women and 40 men) with an average age of 57 ± 25 years and gave up the diagnosis of type and subtypes of anemia in these population. The average concentration of haemoglobin in these patients had a lower worth in men than in women, representing mostly mild anemia in women and moderate in men. The population is mainly characterized by microcitic-hipochromic anemia. In this group found that the majority of population was carrying an iron and ferritin decreased, suggesting that the majority of this group of patients suffering from ferropenic anemia. In the group normocitic-normochromic, ferropenic anemia was the most abundant in women and chronic disease anemia in men. The macrocitic anemia were very rare. The population is now mostly composed of ferropenic anemia (49,5% of patients), which presented concentrations of iron and ferritin lowest, 19,79 ± 7,64 µg/dl and 6,75 ± 3,48 µg/dl respectively, thalassemias in 16,2% of patients and chronic diseases (12,1% of patients), which has the highest ferritin (413,14 ± 218,99 µg/dl).
Description
Relatório de estágio de licenciatura, Bioquímica, Faculdade de Ciências e Tecnologias da Universidade do Algarve, 2007/2008
Keywords
Análises clinicas Anemia