Percorrer por autor "Goncalves, Sandra"
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- Cactus: chemical, nutraceutical composition and potential bio-pharmacological propertiesPublication . Das, Gitishree; Lim, Kyung Jik; Tantengco, Ourlad Alzeus G.; Carag, Harold M.; Goncalves, Sandra; Romano, Anabela; Das, Swagat Kumar; Coy-Barrera, Ericsson; Shin, Han-Seung; Gutierrez-Grijalva, Erick Paul; Heredia, J. Basilio; Patra, Jayanta KumarCactus species are plants that grow in the arid and semiarid regions of the world. They have long fascinated the attention of the scientific community due to their unusual biology. Cactus species are used for a variety of purposes, such as food, fodder, ornamental, and as medicinal plants. In the last regard, they have been used in traditional medicine for eras by the ancient people to cure several diseases. Recent scientific investigations suggest that cactus materials may be used as a source of naturally-occurring products, such as mucilage, fiber, pigments, and antioxidants. For this reason, numerous species under this family are becoming endangered and extinct. This review provides an overview of the habitat, classification, phytochemistry, chemical constituents, extraction and isolation of bioactive compounds, nutritional and pharmacological potential with pre-clinical and clinical studies of different Cactus species. Furthermore, conservation strategies for the ornamental and endangered species have also been discussed.
- Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean dietPublication . Goncalves, Sandra; Moreira, Elsa; Grosso, C.; Andrade, Paula B.; Valentao, Patricia; Romano, AnabelaThe antioxidant and enzyme inhibitory properties of methanolic extracts from four aromatic plants used in traditional medicine and food [Calamintha nepeta (L.) Savi subsp. nepeta, Helichrysum italicum subsp. picardii Franco, Mentha spicata L. and Origanum vulgare subsp. virens (Hoffmanns. & Link) Bonnier & Layens] were evaluated. The extract from O. vulgare exhibited the strongest DPPH (IC50 of 4.65 +/- 0.12 mu g/ml) and ABTS (1479.56 +/- 12.29 mu mol(TE)/g(extract)) scavenging capacities, as well as the largest ferric reducing ability (1746.76 +/- 45.11 mu mol(AAE)/g(extract)). This extract also showed the highest total phenolic content (1597.20 +/- 24.10 mu mol(GAE)/g(extract)) and although HPLC-DAD analysis revealed rosmarinic acid as the main compound of the extract, other compounds seem to be involved in the antioxidant activity. Furthermore, the extract from H. italicum, which was found to be rich in caffeoylquinic and dicaffeoylquinic acids and in pinocembrin, showed the highest inhibitory potential against acetylcholinesterase, tyrosinase and alpha-glucosidase. Overall, the results obtained validate the usefulness of the studied plants as valuable sources of natural agents beneficial for human health.