Browsing by Author "Heredia, J. Basilio"
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- Anti-obesogenic effects of plant natural products: A focus on Korean traditional foodsPublication . Das, Gitishree; Jiménez Ortega, Luis Alfonso; Gonçalves, Sandra; Heredia, J. Basilio; Pereira, Maria de Lourdes Gomes; Shin, Han-Seung; Romano, Anabela; Jayanta Kumar PatraNatural products from food can play an important role in obesity management. Korean traditional food (KTF), characterized by a high inclusion of fresh or prepared vegetables, a reasonable contribution of fish, pulses, and with very little amount of meat, is one of the most recognized cuisines for its nutritional quality, diversity, and flavor. The traditional Korean food contains relevant phytochemicals and probiotic microorganisms with anticancer, anti-mutagenic, antioxidant, and anti-obesogenic properties. Scope: Obesity is a chronic degenerative pathology which causes adverse effects on health, low quality of life, and social costs. The use of fermentation as a conservation/preparation method increases the functional value of KTF, conferring new medicinal properties such as anti-obesogenic. Key findings and conclusions: This review article summarizes data about the anti-obesogenic properties of phytochemicals and KTF. Reviewed results indicated that several phytochemicals present in KTF (e.g., flavonoids, saponins, terpenes) exerted anti-obesogenic effects due to their antioxidant, anti-inflammatory, inhibition of enzymes related to lipid and carbohydrate metabolism, inflection of lipid homeostasis, thermogenic, life cycle of adipocyte, and appetite suppression. Besides, both in vivo and medical research have showed that fermented products extensively included in KTF have a positive effect on the reduction of obesity through different mechanisms particularly by altering human metabolism and affecting gut microbiota. Some molecular mechanisms among these anti-obesogenic agents, are referred in research, focused on the search for phytochemicals that can intervene with leptin sensitizers, GLP1/glucagon dual agonists, GIP/GLP1/glucagon tri-agonists, amylin/calcitonin dual agonists, Y2R agonists, GIP/GLP1 dual agonists, drugs targeting the ghrelin pathway, and GLP1R agonists. Overall, the current review highlights the anti-obesogenic impact of KTF in accordance with the low rate of obesity in the Korean population.
- Cactus: chemical, nutraceutical composition and potential bio-pharmacological propertiesPublication . Das, Gitishree; Lim, Kyung Jik; Tantengco, Ourlad Alzeus G.; Carag, Harold M.; Goncalves, Sandra; Romano, Anabela; Das, Swagat Kumar; Coy-Barrera, Ericsson; Shin, Han-Seung; Gutierrez-Grijalva, Erick Paul; Heredia, J. Basilio; Patra, Jayanta KumarCactus species are plants that grow in the arid and semiarid regions of the world. They have long fascinated the attention of the scientific community due to their unusual biology. Cactus species are used for a variety of purposes, such as food, fodder, ornamental, and as medicinal plants. In the last regard, they have been used in traditional medicine for eras by the ancient people to cure several diseases. Recent scientific investigations suggest that cactus materials may be used as a source of naturally-occurring products, such as mucilage, fiber, pigments, and antioxidants. For this reason, numerous species under this family are becoming endangered and extinct. This review provides an overview of the habitat, classification, phytochemistry, chemical constituents, extraction and isolation of bioactive compounds, nutritional and pharmacological potential with pre-clinical and clinical studies of different Cactus species. Furthermore, conservation strategies for the ornamental and endangered species have also been discussed.
- Galangal, the multipotent super spices: A comprehensive reviewPublication . Das, Gitishree; Patra, Jayanta Kumar; Gonçalves, Sandra; Romano, Anabela; Gutierrez-Grijalva, Erick P.; Heredia, J. Basilio; Das Talukdar, Anupam; Shome, Soumitra; Shin, Han-SeungBackground: Galangal is highly appreciated for its potential applications in food and medicine. In spite of its usage in food and herbal medicine in countries like Indonesia and Thailand, very limited data is accessible about its potential applications in therapeutics and pharmacology. It has been reported to be utilized in herbal medicines for treatment against diseases like hemorrhoids, abnormal menstruation, abdominal discomfort, and inflammation, among others. Scope and approach: The widespread use of galangal in food and traditional medicine has fascinated researchers all over the world looking for its enhanced medicinal capabilities, new bioactive compounds with nutraceutical potentials, and probable uses in medicine and pharmacology. A number of literature search methods like searching the related contents with the keywords such as Alpinia sp., galangal, antiviral, cardiovascular, neuroprotective, bioactive compounds, phytochemicals etc. in the web search engines' such as the Google search, Web of Science, Scopus, PubMed etc. were implemented. Key findings and conclusions: Conversely, there is no recent structured and ample review that summarizes the available data on these issues. In the current review, these topics are addressed in detail along with the investigation of scientific evidence supporting the vast applications of galangal in food and its medicinal properties, such as antiviral, cardiovascular and neuroprotective properties, together with the preclinical and clinical studies with galangal bioactive compounds.