Browsing by Author "Liu, Yu-Zhu"
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- Complete genome of a marine bacterium Vibrio chagasii ECSMB14107 with the ability to infect musselsPublication . Liang, Xiao; Wang, Jin-Song; Liu, Yu-Zhu; Peng, Li-Hua; Li, Yi-Feng; Batista, Frederico; Power, Deborah; Gui, Lang; Yang, Jin-LongVibrio strains are pervasive in the aquatic environment and may form pathogenic and symbiotic relationships with the host. Vibrio chagasii ECSMB14107 was isolated from natural biofilms and is used as a model to elucidate the role of Vibrio in hard-shelled mussel (Mytilus coruscus) settlement, health and disease. The genome of the Vibrio strain ECSMB14107, comprised of two circular chromosomes that together encompass 5,549,357 bp with a mean GC content of 44.39% was determined. Knowledge about the genome of V. chagasii ECSMB14107 will provide insight into its contribution to mussel development and health.
- Two toll-like receptors identified in the mantle of Mytilus coruscus are abundant in haemocytesPublication . Li, Yi-Feng; Liu, Yu-Zhu; Chen, Yan-Wen; Chen, Ke; Batista, Frederico; Cardoso, João CR; Chen, Yu-Ru; Peng, Li-Hua; Zhang, Ya; Zhu, You-Ting; Liang, Xiao; Power, Deborah; Yang, Jin-LongToll-like receptors (TLRs) are a large family of pattern recognition receptors (PREs) that play a critical role in innate immunity. TLRs are activated when they recognize microbial associated molecular patterns (MAMPs) of bacteria, viruses, or fungus. In the present study, two TLRs were isolated from the mantle of the hard-shelled mussel (Mytilus coruscus) and designated McTLR2 and McTLR3 based on their sequence similarity and phylogenetic clustering with Crassostrea gigas, CgiTLR2 and CgiTLR3, respectively. Quantitative RT-PCR analysis demonstrated that McTLR2 and McTLR3 were constitutively expressed in many tissues but at low abundance.