Percorrer por autor "Llopis, Juan"
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- Emerging topics in metal complexes: Pharmacological activityPublication . Ścibior, Agnieszka; Aureliano, Manuel; Llopis, JuanThis Special Issue (SI), ”Emerging Topics in Metal Complexes: Pharmacological Activity”, includes reports updating our knowledge on metals with multidirectional biological properties and metal-containing compounds/complexes for their potential therapeutic applications, with a focus on strategies improving their pharmacological features. The current SI also refers to the biofortification process, which, in the near future, may become a promising source of dietary enrichment with elements important for human health. The scientific articles making up the current SI, i.e., one review and eight original papers (nine in total), garnered a total of six citations and over 8600 visualizations (April 2024). A graphical summary of the content included in this Special Issue is presented in Figure 1, showing a central image with seven hexagons reflecting the seven papers on antitumor, antimicrobial, antioxidant, and CT-imaging properties, flanked by one hexagon each side for the biofortification of wheat sprouts with iron (Fe), zinc (Zn), magnesium (Mg), and chromium (Cr), which can effectively stimulate plant growth (right) and by the influence of vanadium (V) in human neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) (left).
- Metals and metal complexes in diseases with a focus on COVID-19: facts and opinionsPublication . Ścibior, Agnieszka; Aureliano, Manuel; Holder, Alvin A.; Llopis, JuanIn the present Special Issue on “Metals and Metal Complexes in Diseases with a Focus on COVID-19: Facts and Opinions”, an attempt has been made to include reports updating our knowledge of elements considered to be potential candidates for therapeutic applications and certain metal-containing species, which are extensively being examined towards their potential biomedical use due to their specific physicochemical properties [...]
- Special issue “medical value of metal complexes and plant-derived compounds: biological evaluation, health effects, challenges, and future opportunities”Publication . Ścibior, Agnieszka; Aureliano, Manuel; Llopis, JuanThis Special Issue (SI), titled “Medical Value of Metal Complexes and Plant-Derived Compounds: Biological Evaluation, Health Effects, Challenges, and Future Opportunities”, aims to include reports updating our knowledge about the effects of exposure to prevalent heavy metals in the environment, which adversely affect animal and human health. It also focuses on certain natural plant bioactive compounds with multidirectional biological properties, which can effectively alleviate the toxicity of highly hazardous heavy metals and minimize the negative effects of veterinary drugs widely used in the treatment of food-producing animals, on consumer health. It should be emphasized that substances of plant origin are a very interesting research material both in terms of the diversity of the chemical structures of isolated compounds and their possible therapeutic properties [1,2]. For a long time, there has been considerable interest in biologically active compounds of plant origin due to their potential in preventing the toxic effects of xenobiotics [3]. This is a very important and currently relevant trend associated with the search for effective strategies based on natural origin substances aimed at preventing the harmful effects of xenobiotics or mitigating their toxic effects.
- Special issue: emerging topics in metal complexes: pharmacological activity, 2nd editionPublication . Ścibior, Agnieszka; Aureliano, Manuel; Llopis, JuanThis Special Issue (SI), titled “Emerging Topics in Metal Complexes: Pharmacological Activity, 2nd Edition”, includes reports updating our knowledge about magnesium (Mg) and neurodegeneration, various metal-containing complexes in terms of their potential therapeutic applications (i.e., ruthenium (Ru), platinum (Pt), zinc (Zn), vanadium (V), copper (Cu), magnesium (Mg), and other metal complexes and their mechanisms in treating Alzheimer’s disease (AD)), and the efficacy of platinum (Pt)-based complexes in the treatment of lung cancer. It also includes research into a promising radiotheranostic agent against prostate cancer and a novel Fe(III)-pyridoxal-derivative complex with serum proteins and DNA binding activities. In addition, this SI provides valuable findings on the efficacy of methylene blue (MB) in protecting the heart from doxorubicin (Dox)-induced damage and addresses the identification of key active constituents in Eucommia ulmoides Oliv. leaves (EUOL) against Parkinson’s disease (PD) and their underlying mechanisms. The scientific articles making up this SI, i.e., three review articles and four original papers (seven in total), have garnered a total of 16 citations and 17,528 views, indicating an average of 2 citations and 2,504 views per publication (29 November 2025). Figure 1 summarizes the issues included in this SI.
- Special Issue: Emerging Topics in Metal Complexes: Pharmacological Activity, 2nd Edition.Publication . Ścibior, Agnieszka; Aureliano, Manuel; Llopis, JuanThis Special Issue (SI), titled "Emerging Topics in Metal Complexes: Pharmacological Activity, 2nd Edition", includes reports updating our knowledge about magnesium (Mg) and neurodegeneration, various metal-containing complexes in terms of their potential therapeutic applications (i [...].