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Browsing by Author "Marques, Antonio"

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  • Beyond faith: Biomolecular evidence for changing urban economies in multi‐faith medieval Portugal
    Publication . Toso, Alice; Schifano, Simona; Oxborough, Charlotte; McGrath, Krista; Spindler, Luke; Castro, Anabela; Evangelista, Lucy; Filipe, Vanessa; Gonçalves, Maria João; Marques, Antonio; Mendes da Silva, Inês; Santos, Raquel; Valente, Maria João; McCleery, Iona; Alexander, Michelle
    During the Middle Ages, Portugal witnessed unprecedented socioeconomic and religious changes under transitioning religious political rule. The implications of changing ruling powers for urban food systems and individual diets in medieval Portugal is poorly understood. This study aimed to elucidate the dietary impact of the Islamic and Christian conquests.
    2021-06Journal article Open Access Show more
  • In vitro bioaccessibility of the marine biotoxins okadaic acid, dinophysistoxin-2 and their 7-O-acyl fatty acid ester derivatives in raw and steamed shellfish
    Publication . Manita, Diana; Alves, Ricardo N.; Braga, Ana Catarina; Fogaca, Fabiola H. S.; Marques, Antonio; Reis Costa, Pedro
    Okadaic acid (OA), Dinophysistoxins (DTX1 and DTX2) and their acyl-derivatives (DTX3) are marine toxins responsible for the human diarrhetic shellfish poisoning. To date the amount of toxins ingested from consumption of shellfish has been considered equal to the amount of toxins available for uptake by the human body. The aim of this study is to assess the OA, DTX2 and DTX3 fractions released from raw and steamed mussels and cockles into the digestive fluids (bioaccessibility) using a static in vitro digestion model. Higher bioaccessibility was found in mussels (86 +/- 4%) than in cockles (59 +/- 9%). A significant reduction of ester derivatives of OA and an increase of OA were observed in the bioaccessible fraction of mussel samples, suggesting that DTX3 undergo conversion into their more toxic parent compounds during human digestion. However, similar increase of DTX2 and reduction of the respective acyl derivatives was not observed. Steaming lead to significant reduction of OA and analogues bioaccessibility in both species even though increased concentrations of toxins are obtained after this treatment. Risk assessment based solely on DSP toxins occurrence in seafood can conduct to an overestimation of the exposure and lead to more conservative regulatory measures. (C) 2017 Elsevier Ltd. All rights reserved.
    2017-03Journal article Restricted Show more