Percorrer por autor "Patra, Jayanta Kumar"
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- Cactus: chemical, nutraceutical composition and potential bio-pharmacological propertiesPublication . Das, Gitishree; Lim, Kyung Jik; Tantengco, Ourlad Alzeus G.; Carag, Harold M.; Goncalves, Sandra; Romano, Anabela; Das, Swagat Kumar; Coy-Barrera, Ericsson; Shin, Han-Seung; Gutierrez-Grijalva, Erick Paul; Heredia, J. Basilio; Patra, Jayanta KumarCactus species are plants that grow in the arid and semiarid regions of the world. They have long fascinated the attention of the scientific community due to their unusual biology. Cactus species are used for a variety of purposes, such as food, fodder, ornamental, and as medicinal plants. In the last regard, they have been used in traditional medicine for eras by the ancient people to cure several diseases. Recent scientific investigations suggest that cactus materials may be used as a source of naturally-occurring products, such as mucilage, fiber, pigments, and antioxidants. For this reason, numerous species under this family are becoming endangered and extinct. This review provides an overview of the habitat, classification, phytochemistry, chemical constituents, extraction and isolation of bioactive compounds, nutritional and pharmacological potential with pre-clinical and clinical studies of different Cactus species. Furthermore, conservation strategies for the ornamental and endangered species have also been discussed.
- Cardiovascular protective effect of cinnamon and its major bioactive constituents: An updatePublication . Das, Gitishree; Gonçalves, Sandra; Basilio Heredia, J.; Romano, Anabela; Jiménez-Ortega, Luis Alfonso; Gutiérrez-Grijalva, Erick P.; Shin, Han Seung; Patra, Jayanta KumarCinnamon from the bark of Cinnamomum species is one of the most important spices used worldwide in food and as a traditional medicine for centuries. It has substantial benefits for human health including its protective role on cardiovascular diseases. This review provides an overview of the cardiovascular protective effects of cinna-mon and its major bioactive constituents. Reviewed literature showed sufficient evidence that cinnamon can reduce the risk of cardiovascular diseases, including cardiac ischemia, cardiac hypertrophy, and myocardial infarction. Furthermore, cinnamon exhibited beneficial effects on cardiovascular-related comorbidities like diabetes, and other metabolic disorders, and showed antioxidant and anti-inflammatory effects. Cinnamon contains several bioactive compounds such as phenolics and volatile compounds. Cinnamaldehyde and cinnamic acid are among the main cinnamon compounds with protective effects on cardiovascular diseases through different molecular mechanisms. Although the protective effects of cinnamon and its main compounds have been extensively reported, more preclinical and clinical studies are still required before its use as a biopharmaceutical agent.
- Galangal, the multipotent super spices: A comprehensive reviewPublication . Das, Gitishree; Patra, Jayanta Kumar; Gonçalves, Sandra; Romano, Anabela; Gutierrez-Grijalva, Erick P.; Heredia, J. Basilio; Das Talukdar, Anupam; Shome, Soumitra; Shin, Han-SeungBackground: Galangal is highly appreciated for its potential applications in food and medicine. In spite of its usage in food and herbal medicine in countries like Indonesia and Thailand, very limited data is accessible about its potential applications in therapeutics and pharmacology. It has been reported to be utilized in herbal medicines for treatment against diseases like hemorrhoids, abnormal menstruation, abdominal discomfort, and inflammation, among others. Scope and approach: The widespread use of galangal in food and traditional medicine has fascinated researchers all over the world looking for its enhanced medicinal capabilities, new bioactive compounds with nutraceutical potentials, and probable uses in medicine and pharmacology. A number of literature search methods like searching the related contents with the keywords such as Alpinia sp., galangal, antiviral, cardiovascular, neuroprotective, bioactive compounds, phytochemicals etc. in the web search engines' such as the Google search, Web of Science, Scopus, PubMed etc. were implemented. Key findings and conclusions: Conversely, there is no recent structured and ample review that summarizes the available data on these issues. In the current review, these topics are addressed in detail along with the investigation of scientific evidence supporting the vast applications of galangal in food and its medicinal properties, such as antiviral, cardiovascular and neuroprotective properties, together with the preclinical and clinical studies with galangal bioactive compounds.