Repository logo

Browsing by Author "Pestana, Joana"

Now showing 1 - 2 of 2
  • Dance of the sugar: two case reports of chorea associated with nonketotic hyperglycemia
    Publication . Pereira, Rafaela C.; Emidio, Fábio Caleça; Dias, Ângelo; Saez, Rosário Blanco; Shamasna, Motasem; Pestana, Joana
    Hyperglycemia-induced chorea/ballism is a rare clinical entity that often occurs in the setting of nonketotic hyperglycemia due to poor glycemic control in elderly patients with a diagnosis of type 2 diabetes mellitus (DM). This condition is typically characterized by hemichorea/hemiballism and unique brain imaging findings in the contralateral basal ganglia. Treatment involves the correction of blood glucose, and most cases resolve without additional therapy. Here we report two cases of this condition in which patients with type 2 DM presented with nonketotic hyperglycemia and typical neuroimaging findings. Although rare, clinicians should be aware of this condition in patients with diabetes who present with sudden abnormal movements since its prompt diagnosis and treatment often lead to a favorable outcome.
    2023-03-16Journal article Open access Show more
  • Leukocytoclastic vasculitis with systemic involvement associated with ciprofloxacin therapy: case report and review of the literature.
    Publication . Morgado, Bruno; Madeira, Catarina; Pinto, Joana; Pestana, Joana
    A 71-year-old woman presented with constitutional signs and lower extremity palpable purpura after being prescribed a four-day course of 500 mg of ciprofloxacin two times daily for a gastrointestinal infection. She was admitted for inpatient treatment. During the third hospital day, she presented with an episode of abundant hematemesis while her skin lesions remained unchanged. Upper endoscopy revealed multiple lesions consistent with vasculitis and histological examination of the skin biopsy disclosed a leukocytoclastic vasculitis. The patient was successfully treated with prednisone following ciprofloxacin discontinuation. Complete resolution of the lesions on drug withdrawal strongly suggested drug toxicity, which was further supported by a score of 8 in the NaranjoAdverse Drug Reaction Probability Scale. Awareness that the development of skin and gastrointestinal lesions following administration of ciprofloxacin may be a manifestation of ciprofloxacin-induced vasculitiscan help early detection, treatment, and lead to an overall good prognosis.
    2016-11Journal article Open access Show more