Faculdade de Ciências e Tecnologia
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Browsing Faculdade de Ciências e Tecnologia by Subject "& Untargeted Metabolomics."
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- Searching for Bioactive Compounds in the Microalgae Nanofrustulum shiloiPublication . Nwankpa, Ugonna Darlington; Barreira, Luísa AfonsoHypertension remains the greatest risk factor of cardiovascular diseases (CVDs) and the roles of angiotensin converting enzyme (ACE), oxidative stress and cardiovascular inflammation in its etiology are well established. Current hypertension medications present some side effects such as increased risk of hyperkalemia, dry cough, and angioedema, and thus the search for alternative therapies is needed, especially with the increasing emphasis on natural alternatives. Nanofrustulum shiloi is an understudied microalga, but a sustainable and economic repository of nutritive chemicals such as pigments, poly-unsaturated fatty acids (PUFAs), etc., and has been found to inhibit ACE, in a previous study.