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- Involvement of metallothionein in cadmium accumulation and elimination in the clam ruditapes decussataPublication . Bebianno, Maria João; Serafim, Angela; Rita, M. F.Cadmium is one of the most toxic pollutants in seawater because of its persistence, toxicity and potential for bioaecumulation. It is included on the "black list" of several international agreements established to regulate the input of pollutants into the marine environment (Yeasts and Bewers 1987).