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- Low handgrip strength is associated with falls after the age of 50: findings from the Brazilian longitudinal study of aging (ELSI-Brazil)Publication . Santos, André Pereira dos; Cordeiro, Jéssica Fernanda Correa; Abdalla, Pedro Pugliesi; Bohn, Lucimere; Sebastião, Emerson; Silva, Leonardo Santos Lopes da; Tasinafo-Júnior, Márcio Fernando; Venturini, Ana Cláudia Rossini; Andaki, Alynne Christian Ribeiro; Mendes, Edmar Lacerda; Marcos-Pardo, Pablo Jorge; Mota, Jorge; Dalmo Roberto Lopes Machado; Lopes Machado, Dalmo RobertoAim This study examined the association of low handgrip strength (HGS) for falls in middle-aged adults and older adults every half-decade of life. Methods This cross-sectional study was conducted using the public data from the first wave of the Brazilian Longitudinal Study of Aging (ELSI-Brazil). The participants were allocated into seven age groups 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, and ≥ 80 years. Binary logistic regression analysis was performed to identify the odds ratio (OR) of low HGS to the falls regardless of confounding variables such as sex, balance, gait speed, and total number of health conditions. Results A total of 8,112 participants aged 50–105 years (median = 62.0 years): 3,490 males (median = 60.0 years) and 4,622 females (median = 63.0 years) attended the study. Altogether, 21.5% of participants experienced at least one fall. HGS gradually decreases over each half-decade of life. In addition, low HGS presented a significative OR (p < 0.05) for falls for age groups, until 80 s, even when considering confounding variables. Conclusions Low HGS is associated with falls in middle-aged adults over their 50 s and remained a strong measure of falls across each subsequent half-decade of life, until 80 s.