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Occurrence of Guillain-Barre syndrome during the initial symptomatic phase of COVID-19 disease: coincidence or consequence?

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Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.

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Viral mimicry Neurotropic virus Viral infections Covid-19 Guillain barre syndrome

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