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Malignant myopericytoma: report of a new case and review of the literature

dc.contributor.authorPatrick, Agostini
dc.contributor.authorSoares-de-Almeida, Luis
dc.contributor.authorHeinz, Kutzner
dc.date.accessioned2017-04-07T15:56:55Z
dc.date.available2017-04-07T15:56:55Z
dc.date.issued2016-04
dc.description.abstractMalignant myopericytoma is a rare entity with only 8 cases reported in the English literature. The authors report a case of a 65-year-old man with a slow-growing 8-cm nodule on the right arm. Marginal excision was performed, and a diagnosis of malignant myopericytoma was made based on histopathologic and immunohistochemical aspects. These tumors are characterized by a proliferation of round-to-spindle cells of myoid appearance in a concentric perivascular arrangement, along with malignant cytological findings. By immunochemistry, the cells were positive for smooth muscle actin and negative for desmin, cytokeratin AE1/AE3, S100 protein, Melan-A, p63, CD99, bcl-2, CD10, and STAT-6. No membranous expression of type IV collagen was observed. These tumors are associated with aggressive biological behavior and most develops metastases.
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1097/DAD.0000000000000463
dc.identifier.issn0193-1091
dc.identifier.urihttp://hdl.handle.net/10400.1/9556
dc.language.isoeng
dc.peerreviewedyes
dc.relation.isbasedonWOS:000372348900010
dc.subjectMalignant myopericytoma
dc.subjectPerivascular neoplasm
dc.subjectMyoid
dc.subjectSkin
dc.subjectSoft tissue
dc.titleMalignant myopericytoma: report of a new case and review of the literature
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage311
oaire.citation.issue4
oaire.citation.startPage307
oaire.citation.titleAmerican journal of dermatopathology
oaire.citation.volume38
rcaap.rightsopenAccess
rcaap.typearticle

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