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Leiomyosarcoma of the Inferior Vena Cava: a case report of complete and sustained response with Trabectedin
| dc.contributor.author | Cruz, Andre | |
| dc.contributor.author | Bretes, Luis | |
| dc.contributor.author | Reis, Carlos | |
| dc.contributor.author | Furtado, Irene | |
| dc.date.accessioned | 2017-04-07T15:56:47Z | |
| dc.date.available | 2017-04-07T15:56:47Z | |
| dc.date.issued | 2016-04 | |
| dc.description.abstract | Inferior vena cava leiomyosarcoma is a very rare tumor, accounting for only 0.5% of all soft tissue sarcomas. As the other leyomiosarcomas of vascular origin, they have a poor prognosis, and radical resection with surgical margins free of tumor is the only potentially curative treatment. We present a case of a 46 year-old woman with metastatic inferior vena cava leiomyosarcoma who progressed after anthracyclines and ifosfamide and achieved a complete and sustained response with trabectedin. Beyond progression, the patient started third line treatment with pazopanib. A brief review of literature is also given. This case supports the efectiveness of a recent therapeutic agent, with an impressive progression-free survival in a recurrent metastatic inferior vena cava leiomyosarcoma. | |
| dc.identifier.doi | 10.20344/amp.7211 | |
| dc.identifier.issn | 1646-0758 | |
| dc.identifier.uri | http://hdl.handle.net/10400.1/9526 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.relation.isbasedon | WOS:000376995600010 | |
| dc.title | Leiomyosarcoma of the Inferior Vena Cava: a case report of complete and sustained response with Trabectedin | |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 286 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 284 | |
| oaire.citation.title | Acta Medica Portuguesa | |
| oaire.citation.volume | 29 | |
| rcaap.rights | openAccess | |
| rcaap.type | article |
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