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Differential diagnosis in neuroendocrine neoplasms of the Larynx

2017-05Journal article Restricted access
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dc.contributor.authorHunt, Jennifer L.
dc.contributor.authorFerlito, Alfio
dc.contributor.authorHellquist, Henrik
dc.contributor.authorRinaldo, Alessandra
dc.contributor.authorSkalova, Alena
dc.contributor.authorSlootweg, Pieter J.
dc.contributor.authorWillems, Stefan M.
dc.contributor.authorCardesa, Antonio
dc.date.accessioned2019-11-20T15:07:37Z
dc.date.available2019-11-20T15:07:37Z
dc.date.issued2017-05
dc.description.abstractThe differential diagnosis of neuroendocrine neoplasms of the larynx is broad and includes lesions of epithelial, mesenchymal, and neuroectodermal origin. These lesions have overlapping clinical and pathologic aspects and must be carefully considered in the differential diagnosis of laryngeal neoplasms. The prognosis and treatment are also different among these tumor types, which necessitates making these distinctions clinically. The current literature was reviewed to provide updated information regarding the epithelial-derived tumors, including carcinoid, atypical carcinoid, small cell neuroendocrine carcinomas, large cell neuroendocrine carcinoma, and squamous cell carcinoma with neuroendocrine component. These tumors are compared and contrasted with nonepithelial-derived tumors such as paraganglioma and nonmucosal tumors, such as medullary thyroid carcinoma. The morphologic and cytologic features are discussed, along with helpful immunohistochemical and ancillary investigations.
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1097/PAP.0000000000000147
dc.identifier.issn1072-4109
dc.identifier.issn1533-4031
dc.identifier.urihttp://hdl.handle.net/10400.1/13132
dc.language.isoeng
dc.peerreviewedyes
dc.publisherLippincott Williams & Wilkins
dc.subjectAtypical carcinoid-tumor
dc.subjectSquamous-cell carcinoma
dc.subjectClinical-manifestations
dc.subjectMedullary carcinoma
dc.subjectThyroid-carcinoma
dc.subjectParaganglioma
dc.subjectHead
dc.subjectNeck
dc.subjectPrognosis
dc.subjectClassification
dc.titleDifferential diagnosis in neuroendocrine neoplasms of the Larynx
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage168
oaire.citation.issue3
oaire.citation.startPage161
oaire.citation.titleAdvances in Anatomic Pathology
oaire.citation.volume24
person.familyNameHellquist
person.givenNameHenrik
person.identifier.ciencia-id9C11-221B-93BF
person.identifier.orcid0000-0003-3044-6065
rcaap.rightsrestrictedAccess
rcaap.typearticle
relation.isAuthorOfPublicatione632b82a-cf09-4f9a-b445-9d9a9de47438
relation.isAuthorOfPublication.latestForDiscoverye632b82a-cf09-4f9a-b445-9d9a9de47438

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