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R2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomy

dc.contributor.authorQuesado, João
dc.contributor.authorDias, Lara
dc.contributor.authorPereira-Macedo, Juliana
dc.contributor.authorDuarte-Gamas, Luís
dc.contributor.authorKhairy, Ahmed
dc.contributor.authorPinheiro, Marina
dc.contributor.authorReis, Pedro
dc.contributor.authorAndrade, José P.
dc.contributor.authorRocha-Neves, João
dc.contributor.authorMarreiros, Ana
dc.date.accessioned2023-09-26T14:00:14Z
dc.date.available2023-09-26T14:00:14Z
dc.date.issued2023-08
dc.description.abstractBackground: R2CHA2DS2-VA score has been used to predict short and long-term outcomes in many cardiovascular diseases. This study aims to validate the R2CHA2DS2-VA score as a long-term major adverse cardiovascular events (MACE) predictor after carotid endarterectomy (CEA). Secondary outcomes were also assessed regarding the incidence of all-cause mortality, acute myocardial infarction (AMI), major adverse limb events (MALE), and acute heart failure (AHF).Methods: From January 2012 to December 2021, patients (n 1/4 205) from a Portuguese tertiary care and referral center that underwent CEA with regional anesthesia (RA) for carotid stenosis (CS) were selected from a previously collected prospective database, and a posthoc analysis was performed. Demographics and comorbidities were registered. Clinical adverse events were assessed 30 days after the procedure and in the subsequent long-term surveillance period. Statistical analysis was performed by the Kaplan-Meier method and Cox proportional hazards regression.Results: Of the patients enrolled, 78.5% were males with a mean age of 70.44 & PLUSMN; 8.9 years. Higher scores of R2CHA2DS2-VA were associated with long-term MACE (adjusted hazard ratio (aHR) 1.390; 95% confidence interval (CI) 1.173-1.647); and mortality (aHR 1.295; 95% CI 1.08-1.545). Conclusions: This study demonstrated the potential of the R2CHA2DS2-VA score to predict long-term outcomes, such as AMI, AHF, MACE, and all-cause mortality, in a population of pa-tients submitted to carotid endarterectomy.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.avsg.2023.02.016pt_PT
dc.identifier.eissn1615-5947
dc.identifier.urihttp://hdl.handle.net/10400.1/20016
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectChronic kidney-diseasept_PT
dc.subjectGlomerular-filtration-ratept_PT
dc.subjectCell distribution widthpt_PT
dc.subjectAtrial-fibrillationpt_PT
dc.subjectRegional anesthesiapt_PT
dc.subjectOutcomespt_PT
dc.subjectScorept_PT
dc.subjectThromboembolismpt_PT
dc.subjectManagementpt_PT
dc.subjectStrokept_PT
dc.titleR2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage212pt_PT
oaire.citation.startPage205pt_PT
oaire.citation.titleAnnals of Vascular Surgerypt_PT
oaire.citation.volume94pt_PT
person.familyNameMarreiros
person.givenNameAna
person.identifier.ciencia-id9A12-9450-7051
person.identifier.orcid0000-0001-9410-4772
person.identifier.scopus-author-id57194785077
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc0a8e5da-26ae-42a8-ab04-fa4df4356375
relation.isAuthorOfPublication.latestForDiscoveryc0a8e5da-26ae-42a8-ab04-fa4df4356375

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