Publication
R2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomy
dc.contributor.author | Quesado, João | |
dc.contributor.author | Dias, Lara | |
dc.contributor.author | Pereira-Macedo, Juliana | |
dc.contributor.author | Duarte-Gamas, Luís | |
dc.contributor.author | Khairy, Ahmed | |
dc.contributor.author | Pinheiro, Marina | |
dc.contributor.author | Reis, Pedro | |
dc.contributor.author | Andrade, José P. | |
dc.contributor.author | Rocha-Neves, João | |
dc.contributor.author | Marreiros, Ana | |
dc.date.accessioned | 2023-09-26T14:00:14Z | |
dc.date.available | 2023-09-26T14:00:14Z | |
dc.date.issued | 2023-08 | |
dc.description.abstract | Background: R2CHA2DS2-VA score has been used to predict short and long-term outcomes in many cardiovascular diseases. This study aims to validate the R2CHA2DS2-VA score as a long-term major adverse cardiovascular events (MACE) predictor after carotid endarterectomy (CEA). Secondary outcomes were also assessed regarding the incidence of all-cause mortality, acute myocardial infarction (AMI), major adverse limb events (MALE), and acute heart failure (AHF).Methods: From January 2012 to December 2021, patients (n 1/4 205) from a Portuguese tertiary care and referral center that underwent CEA with regional anesthesia (RA) for carotid stenosis (CS) were selected from a previously collected prospective database, and a posthoc analysis was performed. Demographics and comorbidities were registered. Clinical adverse events were assessed 30 days after the procedure and in the subsequent long-term surveillance period. Statistical analysis was performed by the Kaplan-Meier method and Cox proportional hazards regression.Results: Of the patients enrolled, 78.5% were males with a mean age of 70.44 & PLUSMN; 8.9 years. Higher scores of R2CHA2DS2-VA were associated with long-term MACE (adjusted hazard ratio (aHR) 1.390; 95% confidence interval (CI) 1.173-1.647); and mortality (aHR 1.295; 95% CI 1.08-1.545). Conclusions: This study demonstrated the potential of the R2CHA2DS2-VA score to predict long-term outcomes, such as AMI, AHF, MACE, and all-cause mortality, in a population of pa-tients submitted to carotid endarterectomy. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.doi | 10.1016/j.avsg.2023.02.016 | pt_PT |
dc.identifier.eissn | 1615-5947 | |
dc.identifier.uri | http://hdl.handle.net/10400.1/20016 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.publisher | Elsevier | pt_PT |
dc.subject | Chronic kidney-disease | pt_PT |
dc.subject | Glomerular-filtration-rate | pt_PT |
dc.subject | Cell distribution width | pt_PT |
dc.subject | Atrial-fibrillation | pt_PT |
dc.subject | Regional anesthesia | pt_PT |
dc.subject | Outcomes | pt_PT |
dc.subject | Score | pt_PT |
dc.subject | Thromboembolism | pt_PT |
dc.subject | Management | pt_PT |
dc.subject | Stroke | pt_PT |
dc.title | R2CHA2DS2-VA predictsthe cardiovascular risk after carotid endarterectomy | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.endPage | 212 | pt_PT |
oaire.citation.startPage | 205 | pt_PT |
oaire.citation.title | Annals of Vascular Surgery | pt_PT |
oaire.citation.volume | 94 | pt_PT |
person.familyName | Marreiros | |
person.givenName | Ana | |
person.identifier.ciencia-id | 9A12-9450-7051 | |
person.identifier.orcid | 0000-0001-9410-4772 | |
person.identifier.scopus-author-id | 57194785077 | |
rcaap.rights | restrictedAccess | pt_PT |
rcaap.type | article | pt_PT |
relation.isAuthorOfPublication | c0a8e5da-26ae-42a8-ab04-fa4df4356375 | |
relation.isAuthorOfPublication.latestForDiscovery | c0a8e5da-26ae-42a8-ab04-fa4df4356375 |
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