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Cervical lymph node metastasis in adenoid cystic carcinoma of the larynx: a collective international review

dc.contributor.authorCoca-Pelaz, Andres
dc.contributor.authorBarnes, Leon
dc.contributor.authorRinaldo, Alessandra
dc.contributor.authorCardesa, Antonio
dc.contributor.authorShah, Jatin P.
dc.contributor.authorRodrigo, Juan P.
dc.contributor.authorSuarez, Carlos
dc.contributor.authorEloy, Jean Anderson
dc.contributor.authorBishop, Justin A.
dc.contributor.authorDevaney, Kenneth O.
dc.contributor.authorThompson, Lester D. R.
dc.contributor.authorWenig, Bruce M.
dc.contributor.authorStrojan, Primoz
dc.contributor.authorHamoir, Marc
dc.contributor.authorBradley, Patrick J.
dc.contributor.authorGnepp, Douglas R.
dc.contributor.authorSilver, Carl E.
dc.contributor.authorSlootweg, Pieter J.
dc.contributor.authorTriantafyllou, Asterios
dc.contributor.authorVander Poorten, Vincent
dc.contributor.authorWilliams, Michelle D.
dc.contributor.authorSkalova, Alena
dc.contributor.authorHellquist, Henrik
dc.contributor.authorTeymoortash, Afshin
dc.contributor.authorMedina, Jesus E.
dc.contributor.authorRobbins, K. Thomas
dc.contributor.authorPitman, Karen T.
dc.contributor.authorKowalski, Luiz P.
dc.contributor.authorde Bree, Remco
dc.contributor.authorMendenhall, William M.
dc.contributor.authorTakes, Robert P.
dc.contributor.authorFerlito, Alfio
dc.date.accessioned2017-04-07T15:56:48Z
dc.date.available2017-04-07T15:56:48Z
dc.date.issued2016-04
dc.description.abstractAdenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991-2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.
dc.identifier.doi10.1007/s12325-016-0311-z
dc.identifier.issn0741-238X
dc.identifier.urihttp://hdl.handle.net/10400.1/9530
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Verlag
dc.relation.isbasedonWOS:000374992100005
dc.titleCervical lymph node metastasis in adenoid cystic carcinoma of the larynx: a collective international review
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage579
oaire.citation.issue4
oaire.citation.startPage553
oaire.citation.titleAdvances in Therapy
oaire.citation.volume33
person.familyNameHellquist
person.givenNameHenrik
person.identifier.ciencia-id9C11-221B-93BF
person.identifier.orcid0000-0003-3044-6065
rcaap.rightsopenAccess
rcaap.typearticle
relation.isAuthorOfPublicatione632b82a-cf09-4f9a-b445-9d9a9de47438
relation.isAuthorOfPublication.latestForDiscoverye632b82a-cf09-4f9a-b445-9d9a9de47438

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