Publication
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study
| dc.contributor.author | AlĂŁo, SĂlvia | |
| dc.contributor.author | Conceição, João | |
| dc.contributor.author | Dores, Jorge | |
| dc.contributor.author | Santos, LĂšlita | |
| dc.contributor.author | AraĂșjo, Francisco | |
| dc.contributor.author | Pape, EstevĂŁo | |
| dc.contributor.author | Reis, MĂłnica | |
| dc.contributor.author | Chipepo, Ărcia | |
| dc.contributor.author | Nascimento, Edite | |
| dc.contributor.author | Baptista, Ana Catarina | |
| dc.contributor.author | Pires, Vanessa | |
| dc.contributor.author | Marques, Carlos | |
| dc.contributor.author | Lages, Adriana D S | |
| dc.contributor.author | Pelicano-Romano, JoĂŁo | |
| dc.contributor.author | de Jesus, Paula M | |
| dc.date.accessioned | 2021-02-04T16:12:01Z | |
| dc.date.available | 2021-02-04T16:12:01Z | |
| dc.date.issued | 2021-01-05 | |
| dc.date.updated | 2021-02-01T04:14:49Z | |
| dc.description.abstract | Background We intended to estimate the proportion hypoglycemic/hyperglycemic emergency episodes in treated diabetes mellitus (DM) patients admitted to a hospital ward, and calculate the prevalence of risk factors for hypoglycemia and diabetic complications. Methods In this cross-sectional, multicentered study, the observational data was collected by physicians from patientâs hospitalization to discharge/death. Statistical tests were 2-tailed considering 5% significance level. Results There were 646 ward admissions due to hyperglycemic emergencies and 176 hypoglycemic episodes with a ratio hypoglycemia/hyperglycemia 0.27 for all DM patients. In T2DM patients the ratio was 0.38. These were mainly female (55.1%), functionally dependent (61.4%) and retired/disabled (73.1%). Median age was 75âyears and median duration of disease 11âyears. Half the patients were on insulin-based therapy and 30.1% on secretagogue-based therapy. Approximately 57% of patients needed occasional/full assistance to manage the disease. The most frequent risk factor for hypoglycemia was polypharmacy (85.0%). Hypoglycemia in the 12âmonths before admission was higher in insulin-based therapy patients (66.1%; p =â0.001). Conclusions Hyperglycemic emergencies are the most frequent cause of hospitalization in Portugal, although severe hypoglycemic events represent a health and social problem in elderly/frail patients. There is still the need to optimize therapy in terms of the potential for hypoglycemia in this patient group and a review of anti-hyperglycemic agents to add on to insulin. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Clinical Diabetes and Endocrinology. 2021 Jan 05;7(1):2 | pt_PT |
| dc.identifier.doi | 10.1186/s40842-020-00114-3 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.1/15041 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | BioMed Central | pt_PT |
| dc.rights.holder | The Author(s) | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Diabetes | pt_PT |
| dc.subject | Hypoglycemic episodes | pt_PT |
| dc.subject | Inpatients | pt_PT |
| dc.title | Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 2 | pt_PT |
| oaire.citation.title | Clinical Diabetes and Endocrinology | pt_PT |
| oaire.citation.volume | 7 | pt_PT |
| person.familyName | Baptista | |
| person.givenName | Ana Catarina | |
| person.identifier.ciencia-id | D514-D6F1-88F5 | |
| person.identifier.orcid | 0000-0002-0543-0697 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 77b69f2e-1cf6-4452-b13a-0779dd972b85 | |
| relation.isAuthorOfPublication.latestForDiscovery | 77b69f2e-1cf6-4452-b13a-0779dd972b85 |