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Qualidade de vida relacionada com a saúde e satisfação com a vida em idosos da Península Ibérica
Publication . Encarnação, Ana Sofia Coelho; Ferreira, Lara Noronha; Botelho, Marta Cristina Soares
O envelhecimento demográfico tem vindo a ganhar notoriedade na Europa, devido aos desafios que coloca sobre os sistemas de saúde. A Qualidade de Vida Relacionada com a Saúde (QVRS) e da Satisfação com a Vida (SV) são indicadores importantes para avaliar a qualidade do envelhecimento e para auxiliar a gestão em saúde. Apesar destes indicadores serem influenciados por diferentes fatores, não existem estudos que comparem as populações idosas na Península Ibérica, em termos de QVRS e SV. O presente trabalho visa determinar e comparar a QVRS e a SV da população idosa portuguesa e espanhola, assim como identificar os fatores que contribuem para a QVRS e a SV nestas duas populações. Esta investigação pretende inclusive testar a hipótese da existência de uma relação em forma de U entre a SV e a idade e entre a autoperceção de saúde e a idade.
O estudo utilizou dados relativos a 4379 participantes da 6ª vaga do projeto SHARE, que representam a população portuguesa e espanhola com pelo menos 65 anos. Para avaliar a QVRS e a SV, foram utilizadas duas variáveis referentes à autoperceção de saúde e à satisfação com a vida, para as quais foram construídos modelos de regressão ordinal.
Os resultados obtidos indicam que os idosos espanhóis reportam níveis mais altos de QVRS e SV do que os idosos portugueses. Foram também identificados os fatores que contribuem para a QVRS e SV em Portugal e Espanha, sendo que o género, a ausência de cuidados informais e os baixos níveis de depressão foram os fatores que contribuíram positivamente para a QVRS e a SV em ambos os países. O rendimento não teve qualquer influência sobre a QVRS e a SV nos dois países.
As conclusões deste estudo ajudam a identificar as áreas que permitem melhorar o bem-estar dos idosos.
Report of a rare 3q29 interstitial microdeletion: prenatal diagnosis and postnatal follow-up
Publication . Simão, Laurentino; Pedro, Sónia; Marques, Bárbara; Serafim, Sílvia; Ferreira, Cristina; Tarelho, Ana; Brito, Filomena; Silva, Marisa; Alves, Cristina; Viegas, Mónica; Silva, Ana Paula; Rodrigues, Márcia; Ferreira, Ângela; Correia, Hildeberto
Distal interstitial deletions in the 3q29 region are rare. The characterization of new prenatal diagnosis (PND) cases and their follow-up may add knowledge about the affected region.
Multidisciplinary cardiorenal program for heart failure patients: Improving outcomes through comprehensive care
Publication . Calça, Rita; Malho, Anabela; Domingos, Ana Teresa; Fernandes, Raquel Menezes; Silva, Francisca Gomes da; Aguiar, Carlos; Tralhão, António; Ferreira, Jorge; Rodrigues, Anabela; Fonseca, Cândida; Branco, Patrícia
The cardiorenal program (CRP), implemented within a specialized heart failure and kidney disease clinic, encompasses a multidisciplinary approach to the management of patients with heart failure and kidney disease. It focuses on optimizing therapy and improving patient outcomes. The CRP includes a range of services, including clinical evaluation, diagnostic testing, medical treatment, and patient education. The program provides comprehensive care for patients with cardiorenal syndrome, and includes a variety of healthcare professionals, such as cardiologists, nephrologists, pharmacists, and nurses, working together to provide the best possible care. The program also incorporates specific performance indicators to continuously evaluate and improve patient outcomes. The CRP's integrated multidisciplinary care and patient-centered approach is promising for the management of patients with cardiorenal syndrome. (c) 2025 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).
Predictive factors for improved diagnostic accuracy with the use of radial-probe EBUS
Publication . Barroso1, Andreia; Lin, Flávia; Carrondo, Maria Cristina; Palomino, Addy; Demarzo, Sergio Eduardo; Figueiredo, Viviane Rossi; Jacomelli, Marcia
To assess predictive factors for improved diagnostic accuracy with the use of radial-probe EBUS (RP-EBUS). Methods: This was a retrospective review of consecutive patients undergoing RP-EBUS between February of 2012 and January of 2020. Parameters including the presence of a bronchus sign on CT scans, the position of the radial EBUS probe, lesion size, lesion location, and lesion type were analyzed in relation to two defined outcomes (final diagnosis or no diagnosis). Univariate analysis was used in order to explore the individual effects of each parameter on diagnostic accuracy. Multivariate logistic regression was performed to identify significant predictors of diagnostic accuracy. Results: RP-EBUS was used for diagnostic purposes in 101 patients. The lesion was < 3 cm in size in 59 patients (58.4%) and predominantly solid in 60.3%. There was a positive correlation between radial EBUS probe position and diagnostic accuracy (p = 0.036), with 80.9% of the patients showing a bronchus sign on CT scans. Furthermore, 89% of the patients showed a bronchus sign on CT scans and a correlation with diagnostic accuracy (p = 0.030), with 65.8% of the lesions being located in the left/right upper lobe (p = 0.046). When the radial EBUS probe was within the target lesion, the diagnostic yield was = 80.8%. When the probe was adjacent to the lesion, the diagnostic yield was = 19.2%. A bronchus sign on CT scans was the only parameter that independently influenced diagnostic accuracy (adjusted OR, 3.20; 95% CI, 1.081-9.770; p = 0.036). Conclusions: A bronchus sign on CT scans is a powerful predictor of successful diagnosis by RP-EBUS.
A long photoperiod following a short one, and low temperature, stimulate gametogenesis in the sea cucumber Holothuria arguinensis
Publication . Marquet, Nathalie; Canario, Adelino
Temperature and photoperiod are critical regulators of reproduction. However, few studies have evaluated experimentally their specific effects on gametogenesis in sea cucumbers. We tested the effect on gametogenesis of combinations of photoperiod and temperature: "accelerated" (long days following short days; a 12 degrees C deep in temperature), "constant" (constant short photoperiod; constant Spring/Summer temperature) and "natural" conditions (natural photoperiod and temperature). Experiment 1 started in mid-November (after gametogenesis began) and lasted until March. Experiment 2 started in September, after the spawning season (before gametogenesis started), with gonadal biopsy and spawning trials between March and May. In both experiments, the most advanced gonad development was found in accelerated photoperiod and temperature, with more than 50 % of the sea cucumbers reaching maturity and having the longest and thickest gonadal tubules. However, gametogenesis could not progress in sea cucumbers (i.e., shortest and thinnest gonad tubules) under constant short photoperiod combined with accelerated temperature. This indicates that a constant short photoperiod inhibits gametogenesis and that an accelerated thermal cycle cannot trigger gonad development alone. When accelerated photoperiod was combined with either accelerated or constant temperature, gametogenesis progressed, advancing faster in accelerated than constant temperature, with spawning only seen in these two treatments. This highlights that long days following short days are required for gametogenesis and that temperature has a modulatory role rather than a trigger, with a cool winter period being stimulatory. Altogether, our study provides essential information into environmental factors in sea cucumber reproduction, valuable for broodstock management and sustainable aquaculture.