Browsing by Issue Date, starting with "2025"
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- Certification, maintenance and decertification of standardised innovation management systems: Motivations, barriers and benefitsPublication . Mendes de Saboya , Liana; Candido, Carlos Joaquim Farias; Cesário, MarisaThe role of standardised innovation management systems (SIMS) in fostering organisational innovation has been largely overlooked in the literature. This study addresses this gap by investigating the certification, maintenance, and decertification of SIMS. Using a descriptive and inductive methodology, the research analyses primary data from 94 Portuguese organisations with certified SIMS. The findings reveal a strong prevalence of internal motivations for certification, low implementation obstacles, and significant benefits, suggesting that these firms have successfully internalised the SIMS standard into their innovation management processes. Maintenance motivations are also strong, particularly internal ones, which align well with the critical success factors for sustaining certification. The benefits of maintaining SIMS are substantial, particularly internal benefits, as initial external motivations for certification often evolve into internal maintenance motivations. Decertification motivations and propensity are weak among the sample firms. Expectations of negative performance impacts following potential decertification are also low, likely because these organisations have effectively internalised the SIMS standard. This study is the first to explore the maintenance and decertification of SIMS, providing evidence that SIMS can deliver substantial benefits, be efficiently maintained, and continuously enhance innovation and competitiveness. As a result, most organisations exhibit little interest in decertification. The findings offer significant contributions to research and provide actionable insights for practitioners, suggesting that innovation management systems can indeed be standardised with considerable benefits.
- Common mechanistic pathways in rare congenital syndromes with primary microcephalyPublication . Jorge, Xavier; Milagre, Ines; Ferreira, Anita; Calado, Sofia; Oliveira, Raquel; Carvalhal, SaraPrimary microcephaly is an often-seen phenotype in several rare congenital syndromes. It is characterised by a smaller brain size at birth compared to the norm. The causes of this malformation are not fully understood, but genetic testing suggests a connection with defective genes involved in mitotic regulation and proteins related to DNA repair and replication pathways. Cohesinopathies represent a group of rare syndromes, where several subtypes exhibit spontaneous railroad chromosomes and primary microcephaly. This includes Roberts Syndrome, Warsaw Breakage Syndrome and a recently characterised syndrome caused by mutations in the BUB1 gene. Currently, we are examining fibroblast cells from patients with these syndromes to identify common mechanistic pathways. In this context, we have identified a new promising candidate: Topoisomerase II alpha, a protein responsible for resolving of the DNA catenation both in the DNA replication and mitosis. Defective localisation of Topoisomerase II alpha may contribute to the observed mitotic defects in these cells. We are currently exploring the impact of these defects on brain development using reprogramming techniques to assess proper neuronal differentiation.
- RESUPERES Manual intervention proposal for the resilience development in higher education. Overcoming adversitiesPublication . Sousa, Carolina; Cepero González, María Del Mar; Gonçalves, Carla Dionísio; Borges, Maria LeonorIn the 21st century, universities are perceived as spaces that are exposed to social reality and its conflicts. They assume social responsibility which empowers them to respond, with almost certain success, to the demands placed on society, seeking equity and the promotion of justice and solidarity. Students who gain access to university in present society are highly diverse, which increases the urgency with which pedagogy must be made inclusive for all. This will demand that teachers respond to individual differences in order to avoid the exclusion of certain students and will lay the foundation of a sustainable and inclusive university context in which all can learn as long as they are provided with the most suitable conditions for learning (Moriña, 2020). Indeed, many students have reported serious difficulties in terms of access to the Internet due to complex economic situations, either because they cannot afford computer equipment or because poor connectivity is inherent to their place of residence. The impact and presence of technological tools in university classrooms, student-centred teaching approaches, and the increasing presence of students traditionally unrepresented in university spaces, leads to the need to reconsider the role of teachers, underlining comprehensive lifelong training as a way of responding to this new educational reality.
- The first record of Lysmata rauli Laubenheimer and Rhyne, 2010 (Decapoda: Caridea: Lysmatidae) from the tropical eastern AtlanticPublication . Wirtz, Peter; Moura, Carlos; Nhanquê, Filipe T.; Barbosa, Castro; Serrao, Ester A.Here we report the first record of the shrimp Lysmata rauli Laubenheimer and Rhyne, 2010 in the eastern Atlantic, from the intertidal at Kere Island, Bijag & oacute;s archipelago, Guinea-Bissau.
- Otimização de formulações de extrusão de zeólitos recorrendo a planeamento fatorialPublication . Valle, Lívia ; Ferreira, Ricardo; Fernandes, Auguste; Lourenço, João P.; Silva, João M.; João, Isabel M.; Ribeiro, FilipaUm planeamento de experiencias fatorial completo foi utilizado, abrangendo três variáveis independentes em dois níveis, para avaliar os principais parâmetros que influenciam o processo de extrusão. O estudo teve como objetivo otimizar as propriedades do extraído em relação ‡ microporosa ade e ‡ resistência mecânica. As variáveis investigadas incluíram o teor de zeólito (% mássica), a razão ácido/aglomerante (m/m) e a razão base/ácido (m/m). Os resultados para a otimização foram identificados com um valor de dureza Shore D de 33 e um volume microporoso de 0,117 g/cm³.
- Promoting tourism literacy from an educommunicator’s point of viewPublication . Côrtes Moreira, Sandra Cristina; Pérez-Rodríguez, M. Amor; Lopes-Neto, MiguelThis work contributes to the conceptualization of tourism literacy from the approaches of media literacy. In this case, through structured interviews made with Tourism Management Organizations from Algarve, Portugal, we investigate the roles and perceptions of tourism mediators in terms of their relationship with the media and their role as agents of tourism processes from an educommunicative perspective, obtaining relevant information for the systematization of the tourism literacy competence, in terms of the dimensions and indicators for its development.
- Teaching medicine with generative Artificial Intelligence (GenAI): A review of practices, pitfalls, and possibilities in medical educationPublication . Garcia, Manuel B.; Almeida, Rui; Almeida, Raquel Simões de; Acut, Dharel P.; Garcia, Precious S.; Stefani, EleonoraOnce confined to science fiction and speculative futures, generative artificial intel ligence (GenAI) has swiftly entered the lecture halls of modern medical education. Despite its expanding use, a synthesis of its implementation, limitations, and educa tional value remains underexplored. This review aims to critically examine current applications, identify pedagogical pitfalls, and delineate future trajectories for GenAI in medical training. Key innovations include AI-driven content generation tailored to curricular benchmarks, automated assessments with real-time diagnostic feedback, and immersive virtual patient simulations replicating complex pathophysiologies. Additional advances span multilingual knowledge translation, anatomically precise surgical training environments, and adaptive learning systems powered by intelligent tutoring frameworks. As discussed herein, GenAI holds transformative potential for advancing clinical competence in an evolving medical landscape—provided its integration is evidence-based, ethically sound, and educationally coherent.
- Perspectivas luso-brasileiras em artes e comunicaçãoPublication . Fechine, Ingrid; Carrega, Jorge; Araujo, DenizeÉ com entusiasmo que apresentamos o quarto volume da coletânea Perspectivas Luso-Brasileiras em Artes e Comunicação. A publicação é editada pelo Grupo de Pesquisa “Comunicação, Memória e Cultura Popular” da UEPB – Universidade Estadual da Paraíba com o apoio do CIAC – Centro de Investigação em Artes e Comunicação da Universidade do Algarve e CIC – Grupo de Pesquisa “Comunicação, Imagem e Contemporaneidade” da UTP- Universidade Tuiuti do Paraná. A proposta reafirma seu compromisso com a articulação crítica entre pesquisa acadêmica, criação artística e experimentação multimodal, reunindo ensaios que transitam por linguagens diversas e práticas interdisciplinares. O livro propõe um mergulho nos cruzamentos entre arte, tecnologia e memória, refletindo sobre como as experiências contemporâneas de criação reposicionam o tempo e a sensibilidade estética diante de novos dispositivos e plataformas.
- The virome of the panglobal, wide host-range plant pathogen Phytophthora cinnamomi: phylogeography and evolutionary insightsPublication . Botella, Leticia; Hejna, Ondřej; Kudláček, Tomáš; Kovačiková, Kateřina; Rost, Michael; Forgia, Marco; Raco, Milica; Milenković, Ivan; Corcobado, Tamara; Maia, Cristiana; Scanu, Bruno; Drenth, André; Guest, David I; Liew, Edward C Y; Chi, Nguyen Minh; Thu, Pham Quang; Chang, Tun-Tschu; Fu, Chuen-Hsu; Kageyama, Koji; Hieno, Ayaka; Masuja, Hayato; Uematsu, Seiji; Durán, Álvaro; Tarigan, Marthin; Junaid, Muhammad; Nasri, Muhammad; Sanfuentes, Muhammad; Čurn, Vladislav; Webber, Joan F; Brasier, Joan F; Jung, Marília Horta; Jung, ThomasPhytophthora cinnamomi stands out as one of the most devastating plant pathogens worldwide, rapidly expanding its range and impacting a wide range of host species. In this study, we investigated the virome of P. cinnamomi across 222 isolates from Africa, Asia, Europe, Oceania, and the Americas using stranded total RNA sequencing, reverse transcription polymerase chain reaction screening, and Sanger sequencing of selected isolates. Our analysis revealed that virus infections were prevalent across all sampled populations, including RNA viruses associated with the orders Ghabrivirales, Martellivirales, and Tolivirales, and the classes Amabiliviricetes, Bunyaviricetes, and the recently proposed Orpoviricetes. Viruses were mainly found in East and Southeast Asian populations, within the geographic origin of P. cinnamomi but have also spread to new regions where the pathogen has emerged as a clonal destructive pathogen. Among the identified viruses, eight species, including two bunya-like viruses, one narna-like virus, and five ormycoviruses, exhibit a global distribution with some genetic divergence between continents. The interaction between P. cinnamomi and its virome indicates a dynamic coevolution across diverse geographic regions. Indonesia is indicated to be the viral epicentre of P. cinnamomi, with the highest intra- and interspecies diversity of viruses. Viral diversity is significantly enhanced in regions where sexual recombination of P. cinnamomi occurs, while regions with predominantly asexual reproduction harbour fewer viral species. Interestingly, only the partially self-fertile mating type (MAT) A2, associated with the global pandemic, facilitates the spread of viruses across different biogeographic regions, whereas viruses are absent in the self-sterile MAT A1 in its areas of introduction like Australia and South Africa. Intriguingly, the presence of a plant tombusvirus suggests a potential cross-kingdom infection among Chilean isolates and a plant host. This study sheds further light on the geographical origin of P. cinnamomi from a novel virome perspective.
- Computation with real numbers and continuous-time dynamical systemsPublication . Graça, DanielIn this paper we review some results about the interconnections between computation with real numbers and continuous dynamical systems. In particular, we take two complementary approaches: (i) to use standard computational models or theories such as Turing machines or computable analysis to understand which properties of continuous dynamical systems can be computed and (ii) to use continuous dynamical systems directly as models of computation and study their computational power. We will be particularly interested in continuous dynamical systems defined with analytic ordinary differential equations and, in particular, in dynamical systems defined with polynomial ordinary differential equations.