Browsing by Author "Cortes Giraldo, I."
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- Ammoides pusilla (Apiaceae) and Thymus munbyanus (Lamiaceae) from Algeria essential oils: chemical composition, antimicrobial, antioxidant and antiproliferative activitiesPublication . Tefiani, C.; Riazi, A.; Youcefi, F.; S, Azza; Gago, Custódia; Faleiro, Leonor; Pedro, L. G.; Barroso, J. G; Figueiredo, A. C.; Megias, C.; Cortes Giraldo, I.; Vioque, J.; Miguel, Maria GraçaThe chemical composition, and antioxidant, antimicrobial and anti-proliferative activities of the essential oils of Ammoides pusilla (Apiaceae) and Thymus munbyanus (Lamiaceae), collected in Algeria, were studied. Cumin alcohol (44%), p-cymene (18%), limonene (14%), thymol (11%) and gamma-terpinene (7%) predominated in A.pusilla essential oil, whereas carvacrol (71%) was dominant in T.munbyanus essential oil. The antibacterial activity of A.pusilla and T.munbyanus essential oils was studied by the agar diffusion method against Escherichia coli, Salmonella enterica serovar Thyphimurium, methicillin-resistant Staphylococcus aureus and Listeria monocytogenes. The tested bacteria were more susceptible to T.munbyanus essential oil. Ammoides pusilla essential oil was the most effective for scavenging the free radicals. Ammoides pusilla essential oil also had the best reducing power as well as the highest lipid peroxidation inhibition. Thymus munbyanus essential oil showed the best anti-proliferative activity of human acute monocytic leukemia cell line (THP-1).
- Anti-oxidant, Anti-inflammatory and Anti-proliferative Activities of Moroccan Commercial Essential OilsPublication . S, Azza; Lyoussi, B.; Megias, C.; Cortes Giraldo, I.; Vioque, J.; Figueiredo, A. C.; Miguel, Maria GraçaEssential oils (EO) possess antimicrobial, anti-inflammatory, insect repellent, anti-cancer, and antioxidant properties, among others. In the present work, the antioxidant, anti-inflammatory and anti-proliferative activities of Moroccan commercial EOs (Citrus aurantium, C. union, Cupressus sempervirens, Eucalyptus globulus, Foeniculum vulgare and Thymus vulgaris) were evaluated and compared with their main constituents. T. vulgaris EO showed the best free radicals scavenging capacity. This EO was also the most effective against lipid peroxidation along with C. limon and F. vulgare EOs. C. sempervirens EO was the most effective in scavenging NO free radicals, whereas C. limon EO showed the best chelating power. Not all of the major compounds of the EO were responsible for the whole activity of the EOs. T. vulgaris EO showed the best anti-proliferative activity against THP-1 cells in contrast to that of F. vulgare. The antioxidant and anti-inflammatory activities of the EOs were plant species dependent and not always attributable to the EOs main components. Nevertheless, the EOs anti-proliferative activities were more related to their main components, as with T. vulgaris, C. limon, E. globulus and C. sempervirens.