Repository logo

Browsing by Author "Mendes, Tiago"

Now showing 1 - 4 of 4
  • Can Subjective Memory Complaints Identify A beta Positive and A beta Negative Amnestic Mild Cognitive Impairment Patients?
    Publication . Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Maroco, Joao; Silva, Dina; Alves, Luisa; Schmand, Ben; Gerardo, Bianca; Lima, Marisa; Santana, Isabel; de Mendonca, Alexandre
    Background: The use of biomarkers, in particular amyloid-beta (A(beta) changes, has allowed the possibility to identify patients with subjective memory complaints (SMCs) and amnestic mild cognitive impairment (aMCI) who suffer from Alzheimer's disease (AD). Since it is unfeasible that all patients with aMCI could presently undergo biomarkers assessment, it would be important that SMCs might contribute to identify the aMCI patients who have AD amyloid pathology. Objectives: To know whether aMCI patients with amyloid biomarkers (A beta(+)) present greater SMCs as compared to those without amyloid biomarkers (A beta(-)). Methods: Participants were selected from a cohort of nondemented patients with cognitive complaints and a comprehensive neuropsychological evaluation, on the basis of 1) diagnosis of aMCI
    2019Journal article Restricted access Show more
  • MAMMALS in Portugal: A data set of terrestrial, volant, and marine mammal occurrences in Portugal
    Publication . Grilo, Clara; Afonso, Beatriz C.; Afonso, Filipe; Alexandre, Marta; Aliácar, Sara; Almeida, Ana; Alonso, Ivan Prego; Álvares, Francisco; Alves, Paulo; Alves, Paulo Célio; Alves, Pedro; Duarte, Beatriz; Duro, Virginia; Encarnação, Cláudia; Eufrázio, Sofia; Fael, António; Falé, João Salvador; Faria, Sandra; Fernandes, Carlos; Fernandes, Margarida; Lopes, Susana; Rosalino, Luís Miguel; Costa, Gonçalo Ferrão; Ferreira, Clara; Ferreira, Diogo F.; Ferreira, Eduardo; Ferreira, Joaquim Pedro; Ferreira, João; Ferreira, Diana; Fonseca, Carlos; Fontes, Inês; Fragoso, Ricardo; Rosário, Inês T.; López‐Baucells, Adrià; Franco, Claudia; Freitas, Tamira; Gabriel, Sofia I.; Gibb, Rory; Gil, Patricia; Gomes, Carla Patricia Jorge; Horta, Pedro; Gomes, Pedro; Gomes, Verónica; Rossa, Mariana; Grilo, Filipa; Amado, Anabela; Guedes, Américo; Guilherme, Filipa; Gutiérrez, Iván; Harper, Henry; Herrera, José M.; Hipólito, Dário; Infante, Samuel; Jesus, José; Russo, Danilo; Loureiro, Armando; Loureiro, Filipa; Lourenço, Rui; Lourenço, Sofia; Lucas, Paula; Magalhães, Ana; Maldonado, Cristina; Marcolin, Fabio; Marques, Sara; Marques, J. Tiago; Sá, Pedro; Amendoeira, Vitor; Marques, Carina; Marques, Paulo; Marrecas, Pedro Caetano; Martins, Frederico; Martins, Raquel; Mascarenhas, Miguel; Mata, Vanessa A.; Mateus, Ana Rita; Matos, Milene; Sabino‐Marques, Helena; Medinas, Denis; Amorim, Francisco; Mendes, Tiago; Mendes, Gabriel; Mestre, Frederico; Milhinhas, Catarina; Mira, António; Monarca, Rita I.; Monteiro, Norberto; Monteiro, Barbara; Salgueiro, Vânia; Monterroso, Pedro; Nakamura, Mónia; Silva Aparício, Guilherme; Negrões, Nuno; Nóbrega, Eva K.; Nóvoa, Miguel; Nunes, Manuel; Nunes, Nuno Jardim; Oliveira, Flávio; Oliveira, José Miguel; Santos, Helena; Palmeirim, Jorge M.; Pargana, João; Paula, Anabela; Araújo, Ricardo; Paupério, Joana; Pedroso, Nuno M.; Pereira, Guilherme; Pereira, Pedro F.; Pereira, José; Pereira, Maria João Ramos; Santos, Joana; Petrucci‐Fonseca, Francisco; Pimenta, Miguel; Pinto, Sara; Pinto, Nuno; Ascensão, Fernando; Pires, Rosa; Pita, Ricardo; Pontes, Carlos; Quaresma, Marisa; Queirós, João; Barbosa, A. Márcia; Queirós, Luís; Rainho, Ana; Graça Ramalhinho, Maria; Ramalho, Patrícia; Raposeira, Helena; Augusto, Margarida; Rasteiro, Francisco; Rebelo, Hugo; Regala, Frederico Tátá; Reto, Dyana; Jones, Kate E.; Ribeiro, Sérgio Bruno; Rio‐Maior, Helena; Rocha, Ricardo; Rocha, Rita Gomes; Rodrigues, Luísa; Román, Jacinto; Bandeira, Victor; Roque, Sara; Santos, João P. V.; Santos, Nuno; Santos, Sara; Santos, Carlos Pedro; Santos‐Reis, Margarida; Serronha, Ana; Sierra, Pablo; Silva, Bruno; Silva, Carla S. G. M.; Silva, Clara; Laborde, Marina I.; Barbosa, Soraia; Silva, Diogo; Silva, Luís P.; Silva, Ricardo; Silva, Carmen; Silva Júnior, Flavio Manoel Rodrigues; Sousa, Pedro; Sousa‐Guedes, Diana; Spadoni, Giulia; Tapisso, Joaquim T.; Oliveira, Luís Lamas; Teixeira, Daniela; Barbosa, Sérgio; Teixeira, Sérgio; Teixeira, Nuno; Torres, Rita T.; Travassos, Paulo; Vale‐Gonçalves, Hélia; Cidraes‐Vieira, Nuno; Merten, Sophie; Luz Mathias, Maria; Leitão, Inês; Barreiro, Silvia; Barros, Paulo; Barros, Tânia; Barros, Filomena; Basto, Mafalda; Bernardino, Joana; Bicho, Sara; Biedma, Luis Eduardo; Borges, Marta; Braz, Luis; Lemos, Rita; Brito, José Carlos; Brito, Tiago; Cabral, João Alexandre; Calzada, Javier; Camarinha, Cláudia; Carapuço, Mafalda; Cardoso, Paulo; Carmo, Mário; Carrapato, Carlos; Silva Carrilho, Maílis; Lima, Cátia; Carvalho, Diogo Filipe T. C. S.; Carvalho, Filipe; Carvalho, João; Castro, Diana; Castro, Guilherme; Castro, Joana; Castro, Luis Roma; Catry, Filipe Xavier; Cerveira, Ana M.; Cid, André; Linck, Paloma; Clarke, Rafael; Conde, Conceição; Conde, José; Costa, Jorge; Costa, Mafalda; Costa, Pedro; Costa, Cristina; Couto, André Pedro; Craveiro, João; Dias, Marta; Lopes, Hugo; Dias, Sofia
    Mammals are threatened worldwide, with 26% of all species being includedin the IUCN threatened categories. This overall pattern is primarily associatedwith habitat loss or degradation, and human persecution for terrestrial mam-mals, and pollution, open net fishing, climate change, and prey depletion formarine mammals. Mammals play a key role in maintaining ecosystems func-tionality and resilience, and therefore information on their distribution is cru-cial to delineate and support conservation actions. MAMMALS INPORTUGAL is a publicly available data set compiling unpublishedgeoreferenced occurrence records of 92 terrestrial, volant, and marine mam-mals in mainland Portugal and archipelagos of the Azores and Madeira thatincludes 105,026 data entries between 1873 and 2021 (72% of the data occur-ring in 2000 and 2021). The methods used to collect the data were: live obser-vations/captures (43%), sign surveys (35%), camera trapping (16%),bioacoustics surveys (4%) and radiotracking, and inquiries that represent lessthan 1% of the records. The data set includes 13 types of records: (1) burrowsjsoil moundsjtunnel, (2) capture, (3) colony, (4) dead animaljhairjskullsjjaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8),observation in shelters, (9) photo trappingjvideo, (10) predators dietjpelletsjpine cones/nuts, (11) scatjtrackjditch, (12) telemetry and (13) vocalizationjecholocation. The spatial uncertainty of most records ranges between 0 and100 m (76%). Rodentia (n=31,573) has the highest number of records followedby Chiroptera (n=18,857), Carnivora (n=18,594), Lagomorpha (n=17,496),Cetartiodactyla (n=11,568) and Eulipotyphla (n=7008). The data setincludes records of species classified by the IUCN as threatened(e.g.,Oryctolagus cuniculus[n=12,159],Monachus monachus[n=1,512],andLynx pardinus[n=197]). We believe that this data set may stimulate thepublication of other European countries data sets that would certainly contrib-ute to ecology and conservation-related research, and therefore assisting onthe development of more accurate and tailored conservation managementstrategies for each species. There are no copyright restrictions; please cite this data paper when the data are used in publications.
    2022Journal article Open access Show more
  • Memory awareness in patients with Major Depressive Disorder
    Publication . Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Silva, Dina; Alves, Luísa; Schmand, Ben; Simões do Couto, Frederico; Figueira, Maria Luísa; de Mendonça, Alexandre
    Background: Subjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer’s Disease (MCI-AD) and healthy controls (HC). Methods: Patients with MDD (n = 47), MCI-AD (n = 43) and HC (n = 45) were assessed with a self-report memory complaints scale (SMCS) and underwent a comprehensive clinical and neuropsychological assessment. A discrepancy score between the Logical Memory delayed recall and the SMCS total score was calculated as a measure of memory awareness. Results: Patients with MDD (12.5 ± 4.4) and patients with MCI-AD (10.9 ± 4.1) had not significantly different SMCS total scores, whereas HC showed significantly lower scores (4.0 ± 3.0). As much as 74.5% of patients with MDD patients and 65.1% of patients with MCI-AD reported prominent memory complaints, whereas only 4.4% of HC did. Patients with MDD had relatively preserved memory tests, resulting in a higher discrepancy score than both patients with MCI-AD and HC. The SMCS total score correlated positively with depressive symptoms in the 3 groups of participants. Conclusions: Patients with MDD showed inaccurate memory self-awareness as they under-estimated their memory functioning, a pattern distinct from both patients with MCI-AD and HC.
    2021-05Journal article Open access Show more
  • Neuropsychological contribution to predict conversion to dementia in patients with mild cognitive impairment due to Alzheimer's disease
    Publication . Silva, Dina; Cardoso, Sandra; Guerreiro, Manuela; Maroco, Joao; Mendes, Tiago; Alves, Luisa; Nogueira, Joana; Baldeiras, Ines; Santana, Isabel; de Mendonca, Alexandre
    Background: Diagnosis of Alzheimer's disease (AD) confirmed by biomarkers allows the patient to make important life decisions. However, doubt about the fleetness of symptoms progression and future cognitive decline remains. Neuropsychological measures were extensively studied in prediction of time to conversion to dementia for mild cognitive impairment (MCI) patients in the absence of biomarker information. Similar neuropsychological measures might also be useful to predict the progression to dementia in patients with MCI due to AD. Objective: To study the contribution of neuropsychological measures to predict time to conversion to dementia in patients with MCI due to AD. Methods: Patients with MCI due toADwere enrolled from a clinical cohort and the effect of neuropsychological performance on time to conversion to dementia was analyzed. Results: At baseline, converters scored lower than non-converters at measures of verbal initiative, non-verbal reasoning, and episodic memory. The test of non-verbal reasoning was the only statistically significant predictor in a multivariate Cox regression model. A decrease of one standard deviation was associated with 29% of increase in the risk of conversion to dementia. Approximately 50% of patients with more than one standard deviation below the mean in the z score of that test had converted to dementia after 3 years of follow-up. Conclusion: In MCI due to AD, lower performance in a test of non-verbal reasoning was associated with time to conversion to dementia. This test, that reveals little decline in the earlier phases of AD, appears to convey important information concerning conversion to dementia.
    2020Journal article Open access Show more