Browsing by Author "Nau, Werner M."
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- A photoinduced pH jump applied to drug release from cucurbit[7]urilPublication . Carvalho, Cátia Parente; Uzunova, Vanya D.; Silva, José P. da; Nau, Werner M.; Pischel, UweA proof-of-principle for the application of a photoinduced pH jump for delivery of the Hoechst 33258 drug by disassembly of its host-guest complex with cucurbit[7]uril is described.
- Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleasesPublication . Parente Carvalho, Catia; Norouzy, Amir; Ribeiro, Vera; Nau, Werner M.; Pischel, UweCucurbiturils (CB6 and CB7) were shown to inhibit the enzymatically catalyzed restriction of plasmids and linear DNA. This effect can be inverted by supramolecular masking of the macrocycles through competitive complexation with polyamines. These experiments provide supramolecular control of biocatalytic processes.