Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases

Parente Carvalho, Catia; Norouzy, Amir; Ribeiro, Vera; Nau, Werner M.; Pischel, Uwe

http://hdl.handle.net/10400.1/11632

Utilize este identificador para referenciar este registo.

Nome:	Descrição:	Tamanho:	Formato:
Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases.pdf		744.39 KB	Adobe PDF	Ver/Abrir

Contacte-nos

Autores

Parente Carvalho, Catia

Resumo(s)

Cucurbiturils (CB6 and CB7) were shown to inhibit the enzymatically catalyzed restriction of plasmids and linear DNA. This effect can be inverted by supramolecular masking of the macrocycles through competitive complexation with polyamines. These experiments provide supramolecular control of biocatalytic processes.