Browsing by Author "Saraiva, C."
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- Improving non-small-cell lung cancer survival through molecular characterization: Perspective of a multidisciplinary expert panelPublication . Fernandes, M. G. O.; Vilariça, A. S.; Fernandes, B.; Camacho, C.; Saraiva, C.; Estevinho, F.; Bastos, H. Novais e; Lopes, J. M.; Fidalgo, P.; Garrido, P.; Alves, S.; Silva, S.; Sequeira, T.; Barata, F.The management of NSCLC remains challenging, and the integration of data from predictive biomarkers in routine clinical practice can contribute to an optimal, individualized patient approach, particularly given the rapid emergence of effective targeted therapies. When considering molecular biomarker testing, the choice of the biomarker panel, target population, testing approach, and turnaround time are key issues that, when properly addressed, can improve the survival outcomes of NSCLC patients.
- Long COVID-19 fatigue and obstructive sleep apnea: is there a relation?Publication . Pires, L.; Ribeiro, R.; Belchior, I.; Saraiva, C.; Fatal, T.; Guimarães, M. J.; Moniri, Armin; Drummond, M.Fatigue has been reported as the most frequent long COVID-19 symptom. There is a physiological plausibility for relation be tween OSA and long-COVID-19 fatigue, by Intermittent nocturnal hypox emia, endothelial dysfunction, oxidative stress and low grade systemic inflammation. OSA activates the renin-angiotensin-aldosterone system (RAAS) and angiotensin-converting enzyme 2 (ACE2), which is the entry receptor for SARS-CoV-2. The aim of this study is to evaluate if untreated OSA is associated with COVID-19 long-term fatigue.