Percorrer por autor "Vidinha, Joana"
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- Etanercept in the treatment of ankylosing spondylitis and nephrotic syndrome in the context of AA amyloidosis: a 48-month follow-upPublication . Domingos, Ana; Vidinha, Joana; Osorio, Rui; Jerónimo, Teresa; Ribeiro, Célia; Mendonça, Catarina; Góis, Mário; Neves, Pedro LeãoDear Editor, Amyloidosis represents a family of diseases characterized by the deposition of proteinaceous material in the extracellular space that, by forming insoluble clusters on various tissues and organs, affects its function.
- Gaucher disease and Lupus: a rare association?Publication . Jerónimo, Teresa; Cabrita, Ana; Pimentel, Ana; Vidinha, Joana; Fragoso, Andre; Santos, Viriato; Bernardo, Idalecio; Viana, Helena; Carvalho, Fernanda; Brito, Helena; Lazaro, Mario; Neves, Pedro LeaoGaucher disease (GD), is an autosomal recessive lysosomal storage disease that is due to mutations in the glucocerebrosidase (GC) gene, with a prevalence of 1/57,000 to 1/75,000 births worldwide and significantly more common among the Ashkenazi Jewish heritage. GD is categorized into three clinical types4 and the clinical manifestations result from the accumulation of the lipid-laden macrophages in the spleen, liver, bone, bone marrow, leading to impairment of central nervous system in the most severe cases.