Repository logo

Browsing by Issue Date, starting with "2021-08-17"

Filter results by year or month
Now showing 1 - 4 of 4
  • Comparative study of the antioxidant and enzyme inhibitory activities of two types of Moroccan Euphorbia entire honey and their phenolic extracts
    Publication . Boutoub, Oumaima; EL-GUENDOUZ, Soukaina; Manhita, Ana; Dias, Cristina Barrocas; Estevinho, Letícia M.; Paula, Vanessa B.; Carlier, Jorge; Costa, Maria Clara; Rodrigues, Brígida; Raposo, Sara; Aazza, Smail; El Ghadraoui, Lahsen; Miguel, Maria Graça
    Honey is a natural food product very famous for its health benefits for being an important source of antioxidant and phenolic compounds. Euphorbia honeys obtained from different regions of Morocco were evaluated for their ability to inhibit acetylcholinesterase, lipoxygenase, tyrosinase and xanthine oxidase activities. Their antioxidant properties were evaluated using the: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging capacity, nitric oxide scavenging activity (NO) and scavenging ability of superoxide anion radical. Then, the phenolic extracts of the same entire honey samples were evaluated by liquid chromatography coupled to diode array detection and mass spectrometry (LC-DAD-MS) and tested for the biological activities previously evaluated on the entire honeys, in order to conduct a comparative study between both (honey and phenolic extracts). The chromatographic profiles for the studied Euphorbia honey extracts were different. Phenolic compounds gallic acid, 4-hydroxybenzoic acid and p-coumaric acid were detected in all samples, whereas kampferol was only present in two samples. Physicochemical parameters and total phenolic content were also determined. Entire honey that recorded the highest rate of phenols was sample M6 (E. resinifera) = 69.25 mg GAE/100 g. On the other hand, the phenolic extracts had better antioxidant and enzyme inhibitory activities than the entire honeys, regardless the monofloral honey type. In conclusion, the studied Euphorbia honeys may have a great potential as antioxidant, anti-inflammatory and anti-tyrosinase sources for pharmaceutical and cosmetic applications.
    2021-08-17Journal article Open access Show more
  • Stress Echo 2030: the novel ABCDE-(FGLPR) protocol to define the future of imaging
    Publication . Picano, Eugenio; Ciampi, Quirino; Cortigiani, Lauro; Arruda-Olson, Adelaide M.; Borguezan-Daros, Clarissa; de Castro e Silva Pretto, José Luis; Cocchia, Rosangela; Bossone, Eduardo; Merli, Elisa; Kane, Garvan C.; Varga, Albert; Agoston, Gergely; Scali, Maria Chiara; Morrone, Doralisa; Simova, Iana; Samardjieva, Martina; Boshchenko, Alla; Ryabova, Tamara; Vrublevsky, Alexander; Palinkas, Attila; Palinkas, Eszter D.; Sepp, Robert; Torres, Marco A. R.; Villarraga, Hector R.; Preradović, Tamara Kovačević; Citro, Rodolfo; Amor, Miguel; Mosto, Hugo; Salamè, Michael; Leeson, Paul; Mangia, Cristina; Gaibazzi, Nicola; Tuttolomondo, Domenico; Prota, Costantina; Peteiro, Jesus; Van De Heyning, Caroline M.; D’Andrea, Antonello; Rigo, Fausto; Nikolic, Aleksandra; Ostojic, Miodrag; Lowenstein, Jorge; Arbucci, Rosina; Haber, Diego M. Lowenstein; Merlo, Pablo M.; Wierzbowska-Drabik, Karina; Kasprzak, Jaroslaw D.; Haberka, Maciej; Camarozano, Ana Cristina; Ratanasit, Nithima; Mori, Fabio; D’Alfonso, Maria Grazia; Tassetti, Luigi; Milazzo, Alessandra; Olivotto, Iacopo; Marchi, Alberto; Rodriguez-Zanella, Hugo; Zagatina, Angela; Padang, Ratnasari; Dekleva, Milica; Djordievic-Dikic, Ana; Boskovic, Nikola; Tesic, Milorad; Giga, Vojislav; Beleslin, Branko; Di Salvo, Giovanni; Lorenzoni, Valentina; Cameli, Matteo; Mandoli, Giulia Elena; Bombardini, Tonino; Caso, Pio; Celutkiene, Jelena; Barbieri, Andrea; Benfari, Giovanni; Bartolacelli, Ylenia; Malagoli, Alessandro; Bursi, Francesca; Mantovani, Francesca; Villari, Bruno; Russo, Antonello; De Nes, Michele; Carpeggiani, Clara; Monte, Ines; Re, Federica; Cotrim, Carlos; Bilardo, Giuseppe; Saad, Ariel K.; Karuzas, Arnas; Matuliauskas, Dovydas; Colonna, Paolo; Antonini-Canterin, Francesco; Pepi, Mauro; Pellikka, Patricia A.; The Stress Echo 2030 Study Group of the Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI)
    With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD. ABCDE protocol was the fruit of SE 2020, and is the seed of SE 2030, which is articulated in 12 projects: 1-SE in coronary artery disease (SECAD); 2-SE in diastolic heart failure (SEDIA); 3-SE in hypertrophic cardiomyopathy (SEHCA); 4-SE post-chest radiotherapy and chemotherapy (SERA); 5-Artificial intelligence SE evaluation (AI-SEE); 6-Environmental stress echocardiography and air pollution (ESTER); 7-SE in repaired Tetralogy of Fallot (SETOF); 8-SE in post-COVID-19 (SECOV); 9: Recovery by stress echo of conventionally unfit donor good hearts (RESURGE); 10-SE for mitral ischemic regurgitation (SEMIR); 11-SE in valvular heart disease (SEVA); 12-SE for coronary vasospasm (SESPASM). The study aims to recruit in the next 5 years (2021–2025) ≥10,000 patients followed for ≥5 years (up to 2030) from ≥20 quality-controlled laboratories from ≥10 countries. In this COVID-19 era of sustainable health care delivery, SE2030 will provide the evidence to finally recommend SE as the optimal and versatile imaging modality for functional testing anywhere, any time, and in any patient.
    2021-08-17Journal article Open access Show more
  • Volatile profile of Portuguese monofloral honeys: significance in botanical origin determination
    Publication . Machado, Alexandra M.; Antunes, Marília; Miguel, Maria Graça; Vilas-Boas, Miguel; Figueiredo, Ana Cristina
    The volatile profiles of 51 samples from 12 monofloral-labelled Portuguese honey types were assessed. Honeys of bell heather, carob tree, chestnut, eucalyptus, incense, lavender, orange, rape, raspberry, rosemary, sunflower and strawberry tree were collected from several regions from mainland Portugal and from the Azores Islands. When available, the corresponding flower volatiles were comparatively evaluated. Honey volatiles were isolated using two different extraction methods, solid-phase microextraction (SPME) and hydrodistillation (HD), with HD proving to be more effective in the number of volatiles extracted. Agglomerative cluster analysis of honey HD volatiles evidenced two main clusters, one of which had nine sub-clusters. Components grouped by biosynthetic pathway defined alkanes and fatty acids as dominant, namely n-nonadecane, n-heneicosane, n-tricosane and n-pentacosane and palmitic, linoleic and oleic acids. Oxygen-containing monoterpenes, such as cis- and trans-linalool oxide (furanoid), hotrienol and the apocarotenoid α-isophorone, were also present in lower amounts. Aromatic amino acid derivatives were also identified, namely benzene acetaldehyde and 3,4,5-trimethylphenol. Fully grown classification tree analysis allowed the identification of the most relevant volatiles for discriminating the different honey types. Twelve volatile compounds were enough to fully discriminate eleven honey types (92%) according to the botanical origin.
    2021-08-17Journal article Open access Show more
  • Food composition databases: does it matter to human health?
    Publication . Delgado, Amélia; Issaoui, Manel; Vieira, Margarida; Saraiva De Carvalho, Isabel; Fardet, Anthony
    Food provides humans with more than just energy and nutrients, addressing both vital needs and pleasure. Food habits are determined by a wide range of factors, from sensorial stimuli to beliefs and, once commanded by local and seasonal availability, are nowadays driven by marketing campaigns promoting unhealthy and non-sustainable foodstuffs. Top-down and bottom-up changes are transforming food systems, driven by policies on SDGs and by consumer’s concerns about environmental and health impacts. Food quality, in terms of taste, safety, and nutritional value, is determined by its composition, described in food composition databases (FDBs). FDBs are then useful resources to agronomists, food and mechanical engineers, nutritionists, marketers, and others in their efforts to address at maximum human nutrient needs. In this work, we analyse some relevant food composition databases (viz., purpose, type of data, ease of access, regularity of updates), inspecting information on the health and environmental nexus, such as food origin, production mode as well as nutritional quality. The usefulness and limitations of food databases are discussed regarding what concerns sustainable diets, the food ‘matrix effect’, missing compounds, safe processing, and in guiding innovation in foods, as well as in shaping consumers’ perceptions and food choices.
    2021-08-17Journal article Open access Show more