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- Antioxidant and a-amylase inhibition activities of six plants used in the management of diabetes in MoroccoPublication . Aazza, Smail; El-Guendouz, Soukaina; Miguel, Maria da GraçaDiabetes mellitus is one of the major health problems in the world. Conventional antidiabetic drugs are effective; however, they also with unavoidable side effects. On the other hand, plants may be an alternative source of antidiabetic agents. In the present study, six plants (Cynara scolymus, Ceratonia siliqua, Centaurium erythraea, Marrubium vulgare, Salvia officinalis, and Ziziphus lotus reputed for their antidiabetic effect in Moroccan traditional medicine were chosen. The work was focused on the determination of the antioxidant activities by several methods, including as well as their -amylase inhibitory capacity. It was noted that S. officinalis extract contained the highest phenolic contents and the strongest ABTS and nitric oxide scavenging activities. C. erythraea has the highest total flavonoid content and the best total antioxidant activity. M. vulgare showed the best -amylase inhibitory activity and the best chelating power abreast with C. scolymus, which presented very weak antioxidant activities unless good -amylase inhibition. Principal component analysis (PCA) showed a very good correlation between total phenolic content and 2,2-diphenyl-1-picrylhydrazyl (DPPH) along with 2,2'-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radicals scavenging activities. M. vulgare displayed the best α-amylase inhibition capacity.