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- TikTok in higher education: a learning tool to connect with industry and develop students' digital skillsPublication . López-Carril, Samuel; Carpenter, Jeffrey P.; Watanabe, Nicholas M.; Ribeiro, TiagoTikTok has rapidly become a mainstream social media platform, particularly popular among younger populations. However, young people's perceptions of TikTok's use as a teaching–learning tool remain largely unexplored. To address this literature gap, this study involved an educational intervention in which TikTok was integrated into sport management classes at a Spanish university through active learning methodologies. Specifically, it sought to assess changes in students’ perceptions before and after the intervention across three key dimensions: TikTok’s usefulness as a teaching tool, its contribution to professional development, and its potential for industry engagement. To assess students' perceptions of TikTok, a pre-test and post-test were conducted with 48 students (71% male, 29% female) enrolled in the course. Quantitative findings revealed statistically significant positive changes across all three dimensions, suggesting that the intervention positively impacted students’ perceptions of TikTok’s educational, professional, and industry-related value. These findings were reinforced by qualitative data collected through open-ended responses, in which students highlighted TikTok as a creative, motivating, and professionally relevant learning tool. The results of this study offer both theoretical and practical insights that may be valuable to educators and educational institutions considering the strategic integration of social media such as TikTok into higher education.
- Northernmost record of Amphioctopus burryi (Mollusca: Cephalopoda) in the eastern atlantic and molecular confirmation of its amphi-atlantic distributionPublication . Escánez, Alejandro; Roura, Álvaro; Lugo, David; Wirtz, PeterThe tropical brown-striped octopus (Amphioctopus burryi) is recorded for the first time from Madeira Island. Its identification was confirmed through morphological analysis and DNA barcoding molecular techniques. By also analysing specimens from the Canary Islands and Cabo Verde Islands, we provide evidence supporting the amphi-Atlantic distribution of this species. Furthermore, we discuss the potential role of ongoing ocean warming in the expansion of A. burryi in the Canary Islands and its recent record in Madeira Island.
- Mobility of populations in the transition from muslim world to portuguese kingdom in the Algarve, South Portugal, 11th-13th centuriesPublication . Maurer, Anne-France; MacRoberts, Rebecca; López-Aceves, Judith Margarita; Ortega-González, Alvaro Felipe; Relvado, Cláudia; Fernandes, Teresa; Curate, Francisco; Teixeira, João; Roca-Rada, Xavier; Llamas, Bastien; Luzia, Isabel; Pires, Alexandra; Simões Dias de Oliveira, Luís Filipe; Garcia, Cristina Alexandra Tété; Barrocas , Cristina; Schöne, Bernd R.; Ribeiro, Sara; Santos, Jose Francisco; Valente, Maria JoãoThis study investigates mobility during the transition from Muslim to Christian rule in the Algarve, southern Portugal (11th–13th centuries), using multi-isotope analysis to understand population dynamics during this complex conquest period. Skeletal remains from two key populations were analysed: the final Muslims buried in Loulé before the Christian conquest (necropolises of Quinta da Boavista and Hospital da Misericórdia) and the earliest Christians buried in Cacela-aVelha following the Order of Santiago’s capture in 1240 (necropolis of Poço Antigo). Contemporary faunal remains from trash pits and storage silos were also examined (Loulé: Oficina do Senhor Carrilho; Cacela: Silo 7 of Largo da Fortaleza). Strontium, oxygen, and sulphur isotope analysis of human and animal remains were combined with plant sampling for environmental baselines. Machine learning algorithms integrated this data with published Iberian Peninsula plant isotope ratios to create updated strontium isoscape maps, enabling probabilistic geographic assignment of non-local individuals. Ancient DNA analysis of selected Muslim individuals provided additional mobility insights. Results reveal strikingly different mobility patterns. Muslim individuals were largely local (~95%) with a few non-local likely from the Maghreb or eastern Spain. Conversely, the Christian population displayed extensive mobility, greater for males than females, with nearly 50% non-local to the Algarve. Potential origins were diverse and included regions along the Guadiana River and N/ NE areas. While Muslims showed no sex-based isotope mobility patterns, paleogenetic analysis suggested patrilocal social structures and highlight the complex genetic landscape of the region. The overall data showcase a colonisation process poorly documented in other sources.
- Uncovering metabolic vulnerabilities and validation of anti-cancer targetsPublication . Yassuda, Victor; Méndez-Lucas, Andrés; Novellasdemunt, Laura; Coelho, Ana Luísa de SousaCancer is a second leading cause of disease-related death worldwide, with one of its defining hallmarks being the tumor metabolism reprograming to sustain growth and survival. While glucose and glutamine have long been recognized as central nutrients, lipid metabolism has recently emerged as a critical element of this metabolic rewiring. Lipids not only provide a dense source of energy but also supply essential building blocks for membrane biosynthesis, thereby supporting proliferation and adaptation. These roles make lipid metabolism an attractive direction for identifying therapeutic vulnerabilities. Based on previous results from our group, we hypothesize that genetic-enzymatic compensations are responsible for reducing the impact of silencing genes associated with lipid metabolism reestablishing the flux. Therefore, our goal was to develop a strategy to double silence oncogene-induced tumor models in vivo via hydrodynamic transfection. As a complementary strategy, we start the develop of colon cancer organoids through sequential CRISPR editing of APC, TP53, KRAS, and SMAD4.So that the same metabolic targets could be extrapolated to other tissues. In parallel, we refined isotopetracing gas chromatography mass spectrometry (GC-MS) protocols to enable highresolution profiling of both polar and apolar metabolites in cellular and organoid system Pilot studies confirmed the feasibility of dual-shRNA constructs and demonstrated reliable induction of MYC expression in vitro, although in vivo tumor formation remains to be optimized. Colon organoids with triple and quadruple edits showed differential tumorigenicity, consistent with literature, while highlighting the need for refined implantation strategies. Importantly, we established robust isotope-tracing GC-MS protocols capable of detecting elongation products beyond C:20 fatty acids and profiling organoid metabolism. Together, these results provide methodological validation and a solid foundation for future studies aimed at uncovering compensatory mechanisms and metabolic vulnerabilities in cancer.
- O impacto da satisfação com a avaliação do desempenho e da perceção de justiça organizacional na satisfação com a carreira: o papel mediador do comprometimento organizacionalPublication . Carvalho, Maria Madalena Ferreira; Sousa, CátiaA promoção da satisfação com a carreira é uma preocupação crescente nas organizações, sendo reconhecida como um fator determinante para a retenção de talentos, o desenvolvimento profissional e a eficácia das práticas de gestão de recursos humanos. Neste enquadramento, a presente dissertação teve como objetivo analisar de que forma a satisfação com a avaliação do desempenho (AD) e a perceção de justiça organizacional influenciam a satisfação com a carreira, considerando o comprometimento organizacional como variável mediadora. O estudo seguiu uma abordagem quantitativa, tendo sido recolhidos dados através de um questionário online aplicado a uma amostra de 121 trabalhadores portugueses, maioritariamente do sexo feminino (70.2%), com idades entre os 23 e os 68 anos (M = 34.53; DP = 10.23). Foram utilizadas escalas previamente validadas e os dados foram analisados com recurso a correlações, regressões lineares e análises de mediação. Os resultados evidenciaram que tanto a satisfação com a avaliação do desempenho como a perceção de justiça organizacional se associam positivamente à satisfação com a carreira. Verificou-se ainda que o comprometimento organizacional medeia parcialmente estas relações, sublinhando o seu papel na explicação dos mecanismos que ligam as práticas organizacionais à experiência subjetiva de progressão profissional. Os resultados obtidos reforçam a importância de promover processos de avaliação do desempenho mais transparentes, justos e orientados para o desenvolvimento, bem como de fomentar contextos organizacionais que estimulem o vínculo e o envolvimento dos colaboradores.