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- Carlos Ribeiro (1813–1882) e os reconhecimentos geológicos e hidrogeológicos realizados no âmbito do abastecimento de água a Lisboa, a propósito de um documento inéditoPublication . Cardoso, João Luis; Ribeiro, Maria Manuela SimõesApresentam-se novos elementos sobre as investigações de Carlos Ribeiro (1813–1882), enquanto geólogo do recém-criado Ministério das Obras Públicas, relativas à avaliação dos recursos hídricos subterrâneos destinados ao reforço do abastecimento de água a Lisboa, cuja escassez, em meados do século XIX, exigia novas captações. Destacam-se as observações geológicas realizadas em 1856 nas imediações da cidade, registadas em três cadernos com notas, desenhos e observações geológicas e hidrogeológicas inéditas, que serviram de base à monografia publicada pela Academia Real das Ciências de Lisboa em 1857, ano da criação da Segunda Comissão Geológica de Portugal, da qual Ribeiro foi codiretor com Francisco Pereira da Costa. Pioneiro na aplicação da ciência à resolução de problemas públicos, Carlos Ribeiro é considerado o fundador da Hidrogeologia portuguesa, comparável aos melhores da sua época. O trabalho de campo de 1856 permitiu inventariar poços e nascentes, medir caudais, propor obras hidráulicas para reforço do Aqueduto das Águas Livres e cartografar formações geológicas relevantes para a identificação e aproveitamento das camadas aquíferas. Este estudo constitui um notável exemplo da utilização do conhecimento científico em prol do bem comum, antecipando princípios fundamentais da gestão sustentável da água.
- Yeast species associated with industrial cultures of the marine microalgae Tisochrysis lutea: Temperature profiles and auxin productionPublication . Matos, Madalena; Fernandes, Mónica A.; Coelho, Natacha; Santos, Tamara; Varela, João; Rodrigues, Alexandre M. C.; Sá-Correia, IsabelThis study provides the first systematic characterization of culturable yeast diversity associated with large-scale cultivation of Tisochrysis lutea. This marine haptophyte is widely used in aquaculture for its high content of essential fatty acids, pigments, and other bioactive compounds. Culture sampling was conducted at Necton S.A. facilities (Olhão, Portugal) over full production cycles from 5 L flasks until tubular photobioreactors during the months of May and June. The study aimed to identify and isolate the present yeast species and evaluate their physiological traits relevant to potential co-cultivation strategies. All retained isolates belonged to the phylum Basidiomycota, with six species identified: Rhodotorula sphaerocarpa (45%), R. mucilaginosa (20%), R. diobovata (13%), Vishniacozyma carnescens (16%), Naganishia diffluens (3%), and Moesziomyces aphidis (3%). Temperature growth profiles (10–40 °C), tolerance to artificial sea water, and auxin production were characterized, revealing that, except for V. carnescens, the yeast isolates grow optimally at 25–30 °C, within the ideal range for T. lutea cultivation. Results suggest that some of these marine yeasts, particularly R. sphaerocarpa and R. mucilaginosa isolates, could serve as biological enhancers of algal productivity, in situ. This foundational work supports future efforts to develop targeted yeast management or co-cultivation strategies, with the goal of improving biomass yield and metabolite production in industrial T. lutea photobioreactors.
- The building of learning epiphanies in Europe: The influential power of soft law mechanisms in contemporary adult education governancePublication . Barros, RosannaAdopting elements of Global Education Policy and Global Governance theories, our study aims to uncover facets of the influential power embedded in European soft law mechanisms at use in the cross-loading type of Europeanisation, and its role in setting Member States' agenda for contemporary adult education, while establishing its legitimacy. Using a qualitative mode of inquiring, our fieldwork was based on document analysis and an interview. Approaching the object through the political sociology of public action, the research question seeks the linkages between the European Years Initiative, particularly the 2023-2024 European Year of Skills, and the role of expert working groups in spreading a 'policy imaginary' for the building of the European Education Area (EEA) as a learning epiphany. Results reveal aspects of the backstage 'ways of doing things' in the context of multiscale educational governance. A light was shed in the actual processes of 'policy transfer' through global mechanisms based on policy instruments, such as National Coordinators Networks for mutual learning, and in its (over) valorisation of best practices (e.g. coordination practices and dissemination practices). Results also show that the role of Adult Learning in the EEA is currently envisaged as a crucial issue to keep the European way of living, to upskill and reskill, thus adapting workers to new emerging needs, and to improve competitiveness in the global arena.
- Job crafting in hospitality: a systematic literature reviewPublication . Pinheirinho Coelho, Pedro; Viseu, João; Neves de Jesus, SaúlPurpose This study aims to synthesise the empirical evidence on job crafting in hospitality, focusing on its antecedents, mediators, moderators and outcomes. Design/methodology/approach Through the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 27 empirical studies were examined, which were published in peer-reviewed journals between 2001 and 2024, in English and addressing job crafting among hospitality workers. Searches were conducted in Scopus and Web of Science, using thematic analysis to identify key themes and sub-analyses by employee roles. Findings Job crafting was positively related to job satisfaction and performance. It mediated the association between leadership styles, job characteristics, employee and customer behaviours and job satisfaction and performance. Sub-analyses revealed that frontline employees benefit from task and cognitive crafting, while managers excel in relational crafting. Emotional exhaustion persists in low-support contexts. Research limitations/implications The geographical concentration and predominance of cross-sectional designs limit the generalisability of findings. Future research should use mixed-methods approaches and robust designs, focusing on under-represented regions. A proposed research agenda addresses emerging dynamics, e.g. artificial intelligence integration and workforce precarity. Practical implications Hotel establishments should create interventions that allow leaders to develop workers' job crafting skills, which would foster job satisfaction and performance. Originality/value This review presents the nomological network of job crafting in hospitality, presenting its antecedents, mediators, moderators and outcomes. These constructs were aggregated into different categories depending on their nature. Also, it proposes a research agenda contextualised to hospitality's dynamic environment.
- Yeast species associated with industrial cultures of the marine microalgae tisochrysis lutea: temperature profiles and auxin productionPublication . Matos, Madalena; Fernandes, Mónica A.; Coelho, Natacha; Santos, Tamara; Varela, João; Rodrigues, Alexandre M. C.; Sá-Correia, IsabelThis study provides the first systematic characterization of culturable yeast diversity associated with large-scale cultivation of Tisochrysis lutea. This marine haptophyte is widely used in aquaculture for its high content of essential fatty acids, pigments, and other bioactive compounds. Culture sampling was conducted at Necton S.A. facilities (Olhão, Portugal) over full production cycles from 5 L flasks until tubular photobioreactors during the months of May and June. The study aimed to identify and isolate the present yeast species and evaluate their physiological traits relevant to potential co-cultivation strategies. All retained isolates belonged to the phylum Basidiomycota, with six species identified: Rhodotorula sphaerocarpa (45%), R. mucilaginosa (20%), R. diobovata (13%), Vishniacozyma carnescens (16%), Naganishia diffluens (3%), and Moesziomyces aphidis (3%). Temperature growth profiles (10–40 ◦C), tolerance to artificial sea water, and auxin production were characterized, revealing that, except for V. carnescens, the yeast isolates grow optimally at 25–30 ◦C, within the ideal range for T. lutea cultivation. Results suggest that some of these marine yeasts, particularly R. sphaerocarpa and R. mucilaginosa isolates, could serve as biological enhancers of algal productivity, in situ. This foundational work supports future efforts to develop targeted yeast management or co-cultivation strategies, with the goal of improving biomass yield and metabolite production in industrial T. lutea photobioreactors.
- Transforming chronic disease data into actionable knowledge: a comprehensive systematic review for data science models in healthcare knowledge managementPublication . Baptista, Márcia; Vasconcelos, José Braga; Rocha, Álvaro; Silva, Rita; Gouveia, Maria do Carmo Lemos Vieira; Vasconcelos, TiagoThe increasing prevalence of chronic disease, responsible for high mortality and disability, is of considerable concern to healthcare. The ongoing care and management requirements contribute to extreme health costs which affect economies worldwide. Chronic diseases patients require understanding of the existing care models to address their complex and involved health needs. Centers for Disease Control and Prevention shows that providing data to guide, prioritize, deliver and monitor population health is a vital domain to improve Chronic Disease Management. The twenty-first century led to a new age of Data Science and Analytics. Big Data has become a core technology for providing innovative solutions in numerical applications and healthcare services. Embedded in Big Data is valuable information and knowledge. That’s when Data Science becomes an important tool to transform actionable data into knowledge, a requirement to make better decisions, solve complicated problems and optimize health processes. This aims for a Data Science Model as a Healthcare Knowledge Management System tool, which emerges as an important paradigm for innovating healthcare that depends on developing more adaptive, intelligent and user-centric systems that can effectively manage the increasingly dense healthcare knowledge ecosystem. Under this context, there is also a critical need to develop Healthcare Intelligent Systems based on Data Science. This article provides a comprehensive overview of these systems, synthesizing current research and highlighting the critical role of these systems in modern healthcare. It also proposes a model for Healthcare Knowledge Management System based on integrated data science tools transforming healthcare data into actionable knowledge.
- Perturbação de hiperatividade com défice de atenção (ADHD): uma revisão atual e perspetivas sobre o futuro do tratamento farmacológicoPublication . Santos, Hugo Nascimento; Matos, Carlos Adriano Albuquerque Andrade deA perturbação de hiperatividade com défice de atenção (ADHD, do inglês attention deficit hyperactivity disorder) é uma das patologias neurológicas mais prevalentes em pediatria, caracterizando-se por sintomas de inatenção e hiperatividade e/ou impulsividade que conduzem a impedimentos sociais, académicos e profissionais. Compostos ativos derivados da anfetamina como o metilfenidato constituem a terapia farmacológica de primeira linha, devido à sua elevada eficácia na atenuação deste distúrbio. Contudo, limitações tais como efeitos adversos, a potencialização de comorbidades e contraindicações em determinados indivíduos tornam necessária a disponibilidade de alternativas farmacológicas. Alternativas como a atomoxetina e fármacos não estimulantes, como a guanfacina e clonidina, são utilizados como tratamento de segunda linha, no entanto demonstram eficácia inferior e latência de várias semanas no início de ação. Este trabalho de dissertação tem como objetivos a compilação das terapias farmacológicas atualmente aprovados para o tratamento da ADHD, assim como a apresentação de fármacos recentemente aprovados e/ou em desenvolvimento. O trabalho procura comparar estes fármacos quanto ao seu efeito terapêutico, perfil de segurança, e tolerabilidade, de forma a avaliar a possibilidade de uma futura alteração na farmacoterapia deste distúrbio. O desenvolvimento de novos fármacos como a centanafadina e a aprovação da viloxazina para o tratamento deste distúrbio pela FDA refletem o crescente interesse no papel da neurotransmissão serotoninérgica, no controlo da atenção, impulsividade, e regulação emocional. A viloxazina demonstra uma eficácia terapêutica semelhante a outros fármacos de segunda linha, com um perfil de segurança mais favorável comparativamente à atomoxetina. Ensaios clínicos recentes demonstram que a centanafadina apresenta um efeito terapêutico semelhante ao metilfenidato em adultos, com melhor tolerabilidade. No entanto, ensaios comparando estes fármacos diretamente são necessários de forma a aferir sobre os seus efeitos em pediatria a longo prazo. Por outro lado, a aprovação recente da associação serdexmetilfenidato/dexmetilfenidato pela FDA representa uma alternativa de toma única diária a formulações de libertação prolongada de metilfenidato, com um início de ação rápido (30 minutos) e um efeito com uma duração mais prolongada de 13 horas. Palavras-chave: Perturbação de hiperatividade com défice de atenção; Farmacoterapia; Neurofarmacologia; Metilfenidato.