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- New generation oral appliances for treatment of obstructive sleep apneaPublication . Silva, R.; Pires, L.; Belchior, I.; Moniri, ArminOral appliances (OA) have become one of the most important treatments for obstructive sleep apnea (OSA). Efficacy and compliance have been issues raised with this treatment modality. The new generation OAs, using precision technology, are generally smaller devices occupying less space in the mouth. They create less protrusion of the mandible compared to the classical devices. Previous studies on these devices report superior efficacy and compliance. In this study we evaluate the efficiency and compliance of a new generation OA, the Prosomnus EVO, in patients with mild-moderate OSA.
- Long COVID-19 fatigue and obstructive sleep apnea: is there a relation?Publication . Pires, L.; Ribeiro, R.; Belchior, I.; Saraiva, C.; Fatal, T.; Guimarães, M. J.; Moniri, Armin; Drummond, M.Fatigue has been reported as the most frequent long COVID-19 symptom. There is a physiological plausibility for relation be tween OSA and long-COVID-19 fatigue, by Intermittent nocturnal hypox emia, endothelial dysfunction, oxidative stress and low grade systemic inflammation. OSA activates the renin-angiotensin-aldosterone system (RAAS) and angiotensin-converting enzyme 2 (ACE2), which is the entry receptor for SARS-CoV-2. The aim of this study is to evaluate if untreated OSA is associated with COVID-19 long-term fatigue.