Fish as a model organism to study skeletal development and associated pathologies

Gavaia, Paulo J.; Cancela, Leonor

http://hdl.handle.net/10400.1/4385

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Authors

Gavaia, Paulo J.

Cancela, Leonor

Abstract(s)

The physiological and molecular processes that regulate early cell differentiation and maturation, matrix deposition, morphogenesis and maintenance are under strict control during ontogenic skeletal development of vertebrates. A large research effort on the sequencing and genetic characterization of model fish such as zebrafish, medaka, fugu or seabream in the last two decades has provided numerous studies at various levels on the regulation of skeletal formation and demonstrated that similar developmental events occur both in mammalian and non mammalian systems.

URI

http://hdl.handle.net/10400.1/4385

Citation

Paulo J. Gavaia and Leonor Cancela 2008. Fish As A Model Organism To Study Skeletal Development And Associated Pathologies. XXXVII Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq) -XI Congress of the Panamerican Association for Biochemistry and Molecular Biology (PABMB). Águas de Lindóia May 17 to 20, São Paulo, Brazil.